4-Fluoro-2-nitrobenzoic acid

4-Fluoro-2-nitrobenzoic acid Basic information

Product Name:	4-Fluoro-2-nitrobenzoic acid
Synonyms:	BUTTPARK 45\01-65;4-Fluor-2-nitrobenzoesure;Afatinib Impurity 98;2-NITRO-4-FLUOROBENZOIC ACID;RARECHEM AL BO 1973;4-Fluoro-2-Nitrobenzoic Acid 2-Nitro-4-Fluorobenzoic Acid;2 4-Fluoro-2-Nitrobenzoic Acid;4-FLUORO-2-NITROBENZOIC ACID
CAS:	394-01-4
MF:	C7H4FNO4
MW:	185.11
EINECS:	206-890-9
Product Categories:	Aryl Fluorinated Building Blocks;Building Blocks;Carbonyl Compounds;Carboxylic Acids;Chemical Synthesis;Fluorinated Building Blocks;Benzene series;Benzoic acid;C7;Carbonyl Compounds;Carboxylic Acids;Organic Building Blocks;Organic Fluorinated Building Blocks;Other Fluorinated Organic Building Blocks;FINE Chemical & INTERMEDIATES;blocks;Carboxes;FluoroCompounds;NitroCompounds;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
Mol File:	394-01-4.mol

4-Fluoro-2-nitrobenzoic acid Chemical Properties

Melting point	140-145 °C (lit.)
Boiling point	343.8±27.0 °C(Predicted)
density	1.568±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	soluble in Methanol
pka	2.14±0.25(Predicted)
form	powder to crystal
color	White to Light yellow
CAS DataBase Reference	394-01-4(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36/37/39-37
WGK Germany	3
HazardClass	IRRITANT
HS Code	29163990

MSDS Information

Provider	Language
ALFA	English

4-Fluoro-2-nitrobenzoic acid Usage And Synthesis

Chemical Properties	white to light yellow crystal powder
Uses	4-Fluoro-2-nitrobenzoic acid has been used to study the reactions of substituted pyridines with the salicyl phosphate dianion.
Biochem/physiol Actions	4-Fluoro-2-nitrobenzoic acid enhances the binding of insulin to adipocytes.

4-Fluoro-2-nitrobenzoic acid Preparation Products And Raw materials

Raw materials	1-(4-Fluoro-2-nitrophenyl)methanediol 1,1-diacetate-->1,1'-Biphenyl, 4,4'-difluoro-2,2'-dinitro--->4-FLUORO-2-NITRO-BIPHENYL-->BUTTPARK 89\07-47-->4'-FLUORO-2'-NITROACETANILIDE-->4-FLUORO-2-NITROBENZONITRILE-->4-FLUORO-2-NITRO-BENZALDEHYDE-->4-Fluoro-2-nitrotoluene-->4-Fluoro-2-nitrobenzeneamine-->4-Methyl-3-nitroaniline-->Acetic acid
Preparation Products	Entrectinib-->1-BROMO-4-FLUORO-2-NITROBENZENE-->tert-butyl 2-amino-4-(4-methylpiperazin-1-yl)benzoate

4,5-DIFLUORO-2-NITROBENZOIC ACID METHYL ESTER Fluorine 2,4,5-TRIFLUORO-3-METHYL-6-NITROBENZOIC ACID 3-Nitrobenzoic acid 4-Fluoronitrobenzene Methyl 4-fluoro-2-nitrobenzoate 4-FLUORO-2-NITROBENZOIC ACID ETHYL ESTER 4,5-DIFLUORO-2-NITROBENZOIC ACID ETHYL ESTER BUTTPARK 144\07-16 2,4,5-TRIFLUORO-3-METHOXY-6-NITROBENZOIC ACID 4-Nitrobenzoic Acid Isooctyl Ester p-Nitrobenzoic acid 2,3,4,5-TETRAFLUORO-6-NITROBENZOIC ACID 4,5-Difluoro-2-nitrobenzoic acid 4-Fluoro-2-nitrobenzoic acid fluoro jade 1-Fluoro-2-nitrobenzene 2-Nitrobenzoic acid

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