ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyrimidines Aminopyrimidine 5-AMINOPYRIMIDINE

5-AMINOPYRIMIDINE

5-AMINOPYRIMIDINE Basic information
Product Name:5-AMINOPYRIMIDINE
Synonyms:5-AMINOPYRIMIDINE;PYRIMIDIN-5-AMINE;PYRIMIDIN-5-YLAMINE;5-Pyrimidinamine (9CI);5-Pyrimidinamine;5-AMINOPYRIMIDINE (MFCD;Pyrimidin-5-amine, 5-Amino-1,3-diazine;5-Aminopyrimidine >
CAS:591-55-9
MF:C4H5N3
MW:95.1
EINECS:
Product Categories:Heterocycle-Pyrimidine series;PYRIMIDINE;591-55-9
Mol File:591-55-9.mol
5-AMINOPYRIMIDINE Structure
5-AMINOPYRIMIDINE Chemical Properties
Melting point 171°C(lit.)
Boiling point 240.7±13.0 °C(Predicted)
density 1.216±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka2?+-.0.10(Predicted)
form powder to crystal
color White to Light yellow
λmax315nm(EtOH)(lit.)
InChIKeyFVLAYJRLBLHIPV-UHFFFAOYSA-N
Safety Information
Hazard Codes Xi,Xn
Risk Statements 22-36/37/38
Safety Statements 26
WGK Germany 3
HazardClass IRRITANT-HARMFUL
HS Code 2933599590
MSDS Information
5-AMINOPYRIMIDINE Usage And Synthesis
DefinitionChEBI: Pyrimidin-5-amine is an aminopyrimidine.
Purification MethodsIt is purified by conversion to the MgCl2 complex in a small volume of H2O. The complex (~ 5g) is dissolved in the minimum volume of hot H2O, passed through a column of activated Al2O3 (200g), and the column is washed with EtOH. Evaporation of the EtOH gives a colourless residue of the aminopyrimidine which is recrystallised from *C6H6 (toluene could also be used) which forms needles at first, then prisms. It melts with sublimation. Acetylation yields 5-acetamidopyrimidine which crystallises from *C6H6, m 148-149o. [Whittaker J Chem Soc 1565 1951.]
5-AMINOPYRIMIDINE Preparation Products And Raw materials
Raw materialsEthanol-->Sodium nitrite-->Nickel-->2-Methyl-2-thiopseudourea sulfate-->Mucobromic acid-->1-Ethylpiperidine
Preparation ProductsAcetamide, N-5-pyrimidinyl- (9CI)
4-AMINO-2-CHLORO-6-METHYL-5-NITROPYRIMIDINE 2-Amino-5-nitropyrimidine 4,6-DIAMINO-2-MERCAPTO-5-NITROSOPYRIMIDINE 5-Nitroso-2,4,6-triaminopyrimidine 5,6-DIAMINO-2,4-DIHYDROXYPYRIMIDINE SULFATE 4,6-Dichloro-5-aminopyrimidine 4,6-Dichloro-5-nitropyrimidine 4,5,6-TRIAMINOPYRIMIDINE SULFATE 2-AMINO-6,7-DIMETHYL-4-HYDROXY-5,6,7,8-TETRAHYDROPTERIDINE MONOHYDROCHLORIDE 2,4,5,6-Tetraaminopyrimidine sulfate 4,5-Diaminopyrimidine 4,6-DIHYDROXY-5-NITROPYRIMIDINE 2,4-Dichloro-6-methyl-5-nitropyrimidine 4,5-DIAMINO-2-MERCAPTOPYRIMIDINE Calcium folinate 4,5-DIAMINO-6-HYDROXYPYRIMIDINE HEMISULFATE 4,5-DIAMINO-6-HYDROXYPYRIMIDINE SULFATE 4-AMINO-6-HYDROXY-2-MERCAPTO-5-NITROSOPYRIMIDINE
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