L-Glutamic acid 5-tert-butyl ester

L-Glutamic acid 5-tert-butyl ester Basic information

Product Name:	L-Glutamic acid 5-tert-butyl ester
Synonyms:	L-Glutamic acid γ-t.-butyl ester;Glu(OtBu)-OH;L-Glutamic acid γ-tert·butyl ester monohydrate;L-Glutamic acid 5-t-Butyl Ester;GLUTAMIC ACID GAMMA-T-BUTYL ESTER MONOHYDRATE;L-GLUTAMIC ACID-Y-T-BUTYL ESTER;L-GLUTAMIC ACID-Y-T-BUTYLESTER MONOHYDRATE;L-GLUTAMIC ACID .GAMMA.-TERT-BUTYL ESTER MONOHYDRATE
CAS:	2419-56-9
MF:	C9H17NO4
MW:	203.24
EINECS:	607-337-8
Product Categories:	Amino Acids;Glutamic acid [Glu, E];Amino Acids and Derivatives;Amino Acid Derivatives;Glutamic Acid;Peptide Synthesis
Mol File:	2419-56-9.mol

L-Glutamic acid 5-tert-butyl ester Chemical Properties

Melting point	182°C(lit.)
Boiling point	110 °C(Press: 0.05 Torr)
density	0.992 g/cm3
storage temp.	2-8°C
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka	2.20±0.10(Predicted)
form	Solid
color	White to Almost white
Water Solubility	Sparingly soluble in water; practically insoluble in ethanol or ether.
BRN	2049031
CAS DataBase Reference	2419-56-9(CAS DataBase Reference)

Safety Information

MSDS Information

Provider	Language
SigmaAldrich	English

L-Glutamic acid 5-tert-butyl ester Usage And Synthesis

Chemical Properties	White powder crystal
Uses	L-Glutamic acid 5-tert-butyl ester is used as a fine chemical intermediate, pharmaceutical intermediate.

L-Glutamic acid 5-tert-butyl ester Preparation Products And Raw materials

Raw materials	L-GlutaMic acid, 5-(1,1-diMethylethyl) 1-(phenylMethyl) ester-->Z-L-glutamic acid γ-tert·butyl α-benzyl ester-->Cbz-L-Glutamic acid 1-benzyl ester-->Z-GLU(OTBU)-OME-->L-Glutamic acid alpha-benzyl ester-->N-Cbz-L-Glutamic acid 5-tert-butyl ester
Preparation Products	Fmoc-L-glutamic acid 5-tert-butyl ester-->L-Glutamic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-, 25-(1,1-dimethylethyl) ester

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