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| | Mangiferin Basic information |
| Product Name: | Mangiferin | | Synonyms: | 1,3,6,7-tetrahydroxy-2-[(3r,4r,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]xanthen-9-one;1,3,6,7-TETRAHYDROXYXANTHONE-2-C-GLUCOSIDE;1,3,6,7-Tetrahydroxyxanthone C2-beta-D-glucoside;2-beta-d-glucopyranosyl-1,3,6,7-tetrahydroxy-9h-xanthen-9-one;mangiferin from mangifera indica leaves;MANGIFERIN 98% HPLC;Mangiferin90%;2-β-D-Glucopyranosyl-1,3,6,7-tetrahydroxy-9H-xanthen-9-one | | CAS: | 4773-96-0 | | MF: | C19H18O11 | | MW: | 422.34 | | EINECS: | 624-757-7 | | Product Categories: | chemical reagent;pharmaceutical intermediate;The group of Anemarrhenae;The group of Danshen;phytochemical;reference standards from Chinese medicinal herbs (TCM).;Xanthones;standardized herbal extract;Inhibitors;4773-96-0 | | Mol File: | 4773-96-0.mol |  |
| | Mangiferin Chemical Properties |
| Melting point | 269-270°C | | storage temp. | 2-8°C | | solubility | DMSO (Slightly, Sonicated), Methanol (Slightly), Pyridine (Slightly, Heated) | | pKa | 6.09±0.20(Predicted) | | Boiling point | 842.7±65.0 °C(Predicted) | | density | 1.843±0.06 g/cm3(Predicted) | | form | Solid | | color | Pale Yellow | | Stability: | Hygroscopic | | InChIKey | AEDDIBAIWPIIBD-AZBPZEDSNA-N | | SMILES | OC1=C([C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)C(O)=CC2OC3=CC(O)=C(O)C=C3C(=O)C1=2 |&1:3,4,5,7,9,r| | | LogP | 0.130 (est) | | CAS DataBase Reference | 4773-96-0(CAS DataBase Reference) |
| | Mangiferin Usage And Synthesis |
| Chemical Properties | Yellow powder | | Uses | MAO inhibitor, immunostimulant | | Uses | Mangiferin is a xanthonoid, a chemical compound found in mangoes and in Anemarrhena asphodeloides rhizomes. Mangiferin has effect of hepatinica and choleretic, and is used to therapy hepatitis. Mangif
erin is an anti-inflammatory, antivirotic, central nervous system inhibit function and immunologic suppression.
Mangiferin has curative effect on chronic bronchitis. Mangiferin has cytotoxicity effec
t on hepatocellular
carcinoma ce1l, and may induce apoptosis. Mangiferin has the effect of antioxidation and delaying caducity. | | Uses | Mangiferin is a xanthonoid, a chemical compound found in mangoes and in Anemarrhena asphodeloides rhizomes. Mangiferin has effect of hepatinica and choleretic, and is used to therapy hepatitis. Mangiferin is an anti-inflammatory, antivirotic, central nervous system inhibit function and immunologic suppression. Mangiferin has curative effect on chronic bronchitis. Mangiferin has cytotoxicity effect on hepatocellularcarcinoma ce1l, and may induce apoptosis. Mangiferin has the effect of antioxidation and delaying caducity. | | Definition | ChEBI: A C-glycosyl compound consisting of 1,3,6,7-tetrahydroxyxanthen-9-one having a beta-D-glucosyl residue at the 6-position. | | General Description | Mangiferin (MGF) is a natural bioactive polyphenol predominantly isolated from the Mangifera indica (Mango) tree. It has a xanthone glucoside structure. Mangiferin can also be found in other angiosperm plants and herbs. | | Biochem/physiol Actions | Mangiferin has various pharmacological properties including antioxidant, anti-diabetic, anti-bacterial, cardioprotective, neuroprotective, and immunomodulatory activities. It has also displayed antidiabetic, antihyperlipidemic, and antiatherogenic properties in streptozotocin-induced diabetic rats. MGF exerts chemotherapeutic and chemo-preventative activities. It displays antioxidant, analgesic, and hepatoprotective activity against carbon tetrachloride-induced liver injury. MGF is a known accelerator of gastrointestinal transit (GIT). |
| | Mangiferin Preparation Products And Raw materials |
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