CYCLO(-PHE-PRO)

CYCLO(-PHE-PRO) Basic information
Product Name:CYCLO(-PHE-PRO)
Synonyms:(3S-trans)-3-benzylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione;(3S,8aS)-3-Benzyl-6,7,8,8aα-tetrahydropyrrolo[1,2-a]pyrazine-1,4(2H,3H)-dione;(3S,8aS)-3β-Benzyl-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazine-1,4(2H,3H)-dione;(3S,8aα)-3β-Benzyloctahydropyrrolo[1,2-a]pyrazine-1,4-dione;Cyclo(L-Phe-L-Pro-);Cyclo(Pro-Phe-);(3S)-2,3,6,7,8,8aβ-Hexahydro-3β-(phenylmethyl)pyrrolo[1,2-a]pyrazine-1,4-dione;Cyclo(D-Pro-L-Phe-)
CAS:3705-26-8
MF:C14H16N2O2
MW:244.29
EINECS:223-047-0
Product Categories:
Mol File:3705-26-8.mol
CYCLO(-PHE-PRO) Structure
CYCLO(-PHE-PRO) Chemical Properties
Melting point 146-148 °C
Boiling point 509.5±39.0 °C(Predicted)
density 1.26±0.1 g/cm3(Predicted)
storage temp. -15°C
solubility Chloroform (Slightly), Ethanol (Slightly, Sonicated)
pka13.21±0.40(Predicted)
form Solid
color White to Off-White
Stability:Hygroscopic
Safety Information
MSDS Information
CYCLO(-PHE-PRO) Usage And Synthesis
Chemical PropertiesWhite powder
UsesCyclo(L-prolyl-L-phenylalanyl) is a diketopiperazine derivative isolated from Bacillus thuringiensis and Bacillus endophyticus.
UsesCyclo(L-Phe-L-Pro) is a diketopiperazine formed by the fusion of phenylalanine and proline, reported as a secondary metabolite of fungi and bacteria. In Pseudomonas aeruginosa, cyclo(L-Phe-L-Pro) is capable of activating N-acylhomoserine lactones (AHLs). Cyclo(L-Phe-L-Pro) is also capable of activating or antagonizing other LuxR-based quorum-sensing systems. While the mode of action of cyclo(L-Phe-L-Pro) is not known, its activity suggests the existence of cross talk among bacterial signalling systems.
DefinitionChEBI: Cyclo(L-Phe-L-Pro) is an organic molecular entity. It has a role as a metabolite.
CYCLO(-PHE-PRO) Preparation Products And Raw materials
1-(1-Pyrrolidinyl)-2-propanamine ETHYL[(1-METHYLPYRROLIDIN-2-YL)METHYL]AMINE N-methyl-2-pyrrolidin-1-yl-ethanamine 1-PROPYLPIPERAZINE 2-Ethylpiperazine (S,S)-3-BENZYL-1,4-DIAZABICYCLO[4.3.0]NONANE N-[(1-METHYL-2-PYRROLIDINYL)METHYL]-1-PROPANAMINE N1,N1-DIMETHYL-3-PHENYL-1,2-PROPANEDIAMINE 1-Butylpyrrolidine CYCLO(-ALA-ALA) 2-(Aminomethyl)-1-ethylpyrrolidine 2-Methylpiperazine 1-ETHYLPIPERAZIN-2-ONE (R)-HEXAHYDROPYRROLO[1,2-A]PYRAZIN-1(2H)-ONE 1-(2-Aminoethyl)pyrrolidine N1,N1-DIETHYL-3-PHENYL-1,2-PROPANEDIAMINE (S)-1,4-DIAZABICYCLO[4.3.0]NONANE CYCLO(-PHE-PRO)

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