4,5-DIBROMO-O-XYLENE

4,5-DIBROMO-O-XYLENE Basic information
Product Name:4,5-DIBROMO-O-XYLENE
Synonyms:1,2-DIBROMO-4,5-DIMETHYLBENZENE;4,5-DIBROMO-O-XYLENE;4,5-DIBROMO-1,2-DIMETHYLBENZENE;1,2-Dibromo-4,5-dimethylbenzene 98+%;2-Dibromo-4,5-dimethylbenzene;1,2-DiMethyl-4,5-dibroMobenzene;1,2-Dibromo-4,5-dimethylbenzene >;Benzene, 1,2-dibromo-4,5-dimethyl-
CAS:24932-48-7
MF:C8H8Br2
MW:263.96
EINECS:
Product Categories:Halides;Phenyls & Phenyl-Het;Phenyls & Phenyl-Het
Mol File:24932-48-7.mol
4,5-DIBROMO-O-XYLENE Structure
4,5-DIBROMO-O-XYLENE Chemical Properties
Melting point 85-89 °C (lit.)
Boiling point 278 °C
density 1.7485 (rough estimate)
refractive index 1.6146 (estimate)
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
color White to Pale Yellow
BRN 2206183
InChIKeyBCIDDURGCAHERU-UHFFFAOYSA-N
CAS DataBase Reference24932-48-7(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36/37
WGK Germany 3
HazardClass IRRITANT
HS Code 29039990
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
4,5-DIBROMO-O-XYLENE Usage And Synthesis
Chemical PropertiesWhite solid
Uses1,2-Dibromo-4,5-dimethylbenzene is used as a reagent in the synthesis of Thalidomide (T338850); an inhibitor of FGF-induced angiogenesis and replication of human immunodeficiency virus type 1. Also a teratogenic sedative and immunomodulatory agent used primarily in combination with dexamethasone to treat multiple myeloma.
Uses1,2-Dibromo-4,5-dimethylbenzene can be used in the synthesis of alkylamino zinc(II)phthalocyanines, with potential application as photosensitizers in photodynamic therapy. It can also be used in the synthesis of 1,2-dibromo-4,5-bis(dibromomethyl)benzene via reaction with azobisisobutyronitrile.
General Description1,2-Dibromo-4,5-dimethylbenzene can be synthesized via bromination of o-xylene.
4,5-DIBROMO-O-XYLENE Preparation Products And Raw materials
Preparation Products4,5-diMethylphthalonitrile
ALPHA,ALPHA,ALPHA',ALPHA',4,5-HEXABROMO-O-XYLENE 3,4,5,6-TETRABROMO-O-XYLENE DIALLYL TETRABROMOPHTHALATE 3,4,5,6-TETRABROMOPHTHALIMIDE Sulfobromophthalein sodium 2-(2-hydroxyethoxy)ethyl 2-hydroxypropyl 3,4,5,6-tetrabromophthalate bis(2-ethylhexyl) tetrabromophthalate Tetrabromophthalic anhydride 1,2-DIBROMO-3,4,5,6-TETRAMETHYLBENZENE BROMOSULFALEIN 4,5-dibromophthalic acid 4,5,6,7-TETRABROMOPHENOLPHTHALEIN AURORA 17308 TETRABROMOPHTHALIC ACID 4,5,6,7-TETRABROMO-2-(OXIRAN-2-YLMETHYL)ISOINDOLINE-1,3-DIONE 1,2-Bis(tetrabromophthalimido) ethane 3,3'-(4,5,6,7-tetrabromo-3-oxo-1(3H)-isobenzofuranylidene)bis[6-hydroxybenzenesulphonic] acid N,N'-(methylenedi-p-phenylene)bis[3,4,5,6,-tetrabromophthalimide]

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