1-CHLORO-4-IODOBUTANE

1-CHLORO-4-IODOBUTANE Basic information
Product Name:1-CHLORO-4-IODOBUTANE
Synonyms:1-chloro-4-iodo-butan;Butane, 1-chloro-4-iodo-;TETRAMETHYLENE CHLOROIODIDE;1-CHLORO-4-IODOBUTANE;1-IODO-4-CHLOROBUTANE;4-Chlorobutyl iodide;1-Chloro-4-iodobutane (stabilized with Copper chip);4-Iodobutyl chloride, 4-Chlorobutyl iodide
CAS:10297-05-9
MF:C4H8ClI
MW:218.46
EINECS:233-669-4
Product Categories:Organic Building Blocks;Alkyl;Halogenated Hydrocarbons
Mol File:10297-05-9.mol
1-CHLORO-4-IODOBUTANE Structure
1-CHLORO-4-IODOBUTANE Chemical Properties
Melting point 93 °C
Boiling point 88-89 °C/19 mmHg (lit.)
density 1.785 g/mL at 25 °C (lit.)
refractive index n20/D 1.54(lit.)
Fp 200 °F
storage temp. 2-8°C(protect from light)
solubility Chloroform, Ethyl Acetate
form Oil
color Clear Colourless
Specific Gravity1.785
Sensitive Light Sensitive
BRN 1361365
CAS DataBase Reference10297-05-9(CAS DataBase Reference)
EPA Substance Registry SystemButane, 1-chloro-4-iodo- (10297-05-9)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
TSCA Yes
HS Code 29031980
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
1-CHLORO-4-IODOBUTANE Usage And Synthesis
Chemical Propertiesclear yellow to brown liquid
Uses1-Chloro-4-iodobutane may be used in the following studies:
  • Preparation of 6-hendecenoic acid.
  • Catalytic asymmetric synthesis of levobupivacaine.
  • Synthesis of alkaloids such as deoxyvasicinone, mackinazolinone.
Uses1-Chloro-4-iodobutane acts as a reagent in the synthesis of alkyl chromones/quinolones via cyclization/alkylation of enaminones and as an intermediate in many pharmaceutical synthesis.
DefinitionChEBI: 1-Chloro-4-iodobutane is an organoiodine compound.
General Description1-Chloro-4-iodobutane is a halogenated hydrocarbon. It is an α,ω-dihaloalkane and undergoes electrogenerated Nickel(I) salen (N,N′-bis(salicylidene)ethylenediamine) catalyzed reduction to afford 1,8-dichlorooctane. Electrochemical reduction of 1-chloro-4-iodobutane at glassy carbon cathode has been investigated by cyclic voltammetry and controlled-potential electrolysis.
1-CHLORO-4-IODOBUTANE Preparation Products And Raw materials
Preparation Products4-(4-CHLOROBUTYL) PYRIDINE-->1-CHLORO-4-PHENYLBUTANE-->Biphenyl
1-chloro-10-iododecane 1-CHLORO-5-IODOPENTANE 1-CHLORO-2-IODOETHANE 1-CHLORO-6-IODOHEXANE 1-chloro-7-iodoheptane 1-chloro-9-iodononane 1-chloro-8-iodooctane 1-chloro-1-iodomethane 1-CHLORO-3-IODOPROPANE 1-chloro-8-iodooctane 3-IODOMETHYL-HEXANOYL CHLORIDE 1,2-DICHLORO-4-IODOPERFLUOROBUTANE 1-Iodobutane 1-CHLORO-4-IODOBUTANE 1,2-DICHLORO-1,1,2-TRIFLUORO-4-IODOBUTANE

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