Ethylmagnesium bromide

Ethylmagnesium bromide Basic information
Product Name:Ethylmagnesium bromide
Synonyms:bromoethyl-magnesiu;ETHYLMAGNESIUM BROMIDE, CA. 3.2M SOLUTION IN 2-METHYLTETRAHYDROFURAN;Ethylmagnesium bromide, 0.9M solution in tert-butyl methyl ether;Ethylmagnesium bromide1M solution in THFAcroSeal§3;Ethylmagnesium bromide0.9M in tert-Butyl methyl ether;Ethylmagnesium bromide3M in Diethyl etherAcroSeal§3;Ethylbromomagnesium;Ethylmagnesium bromide, 3M in ether, packaged under Argon in resealable ChemSeal^t bottles
CAS:925-90-6
MF:C2H5BrMg
MW:133.27
EINECS:213-127-3
Product Categories:Classes of Metal Compounds;Grignard Reagents;Grignard Reagents & Alkyl Metals;Mg (Magnesium) Compounds;Synthetic Organic Chemistry;Typical Metal Compounds;AlkylChemical Synthesis;Grignard Reagents;Organic Bases;Organometallic Reagents;Synthetic Reagents;Alkyl;Chemical Synthesis;Organometallic Reagents;grignard reagent;925-90-6
Mol File:925-90-6.mol
Ethylmagnesium bromide Structure
Ethylmagnesium bromide Chemical Properties
Melting point -116.3°C
Boiling point 34.6°C
density 1.02 g/mL at 25 °C
Fp <−30 °F
storage temp. water-free area
solubility Miscible in alcohols, ketones, esters, ethers, hydrocarbons.
form Solution
color Pale yellow to brown
Water Solubility Reacts with water.
Sensitive Air & Moisture Sensitive
BRN 3587203
Exposure limitsACGIH: TWA 400 ppm; STEL 500 ppm
OSHA: TWA 400 ppm(1200 mg/m3)
NIOSH: IDLH 1900 ppm
InChIInChI=1S/C2H5.BrH.Mg/c1-2;;/h1H2,2H3;1H;/q;;+1/p-1
InChIKeyTWTWFMUQSOFTRN-UHFFFAOYSA-M
SMILESC(C)[Mg]Br
CAS DataBase Reference925-90-6(CAS DataBase Reference)
EPA Substance Registry SystemMagnesium, bromoethyl- (925-90-6)
Safety Information
Hazard Codes F+,C,F
Risk Statements 12-14/15-19-22-34-66-67-40-11-14-37
Safety Statements 16-26-36/37/39-43-45-7/8-27-9
RIDADR UN 3399 4.3/PG 1
WGK Germany 1
1-3-10
TSCA Yes
HazardClass 4.3
PackingGroup I
HS Code 29319090
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
Ethylmagnesium bromide Usage And Synthesis
Chemical PropertiesEthylmagnesium bromide is generally sold as a dark brown solution and can be dissolved in diethyl ether, butyl ether, isopropyl ether, THF and anisole.
UsesEthylmagnesium Bromide is a useful reagent in preparation of zirconium complexes having two phenoxy-imine chelate ligands for olefin polymerization.
PreparationEthylmagnesium bromide is commercially available, usually as a solution in diethyl ether or tetrahydrofuran. It may be prepared in the normal manner of Grignard reagents — by reacting bromoethane with magnesium in diethyl ether:
EtBr + Mg → EtMgBr
ReactionsEthylmagnesium bromide reacts with water to produce ethane.
CH3CH2MgBr+H2O→CH3-CH3+Mg(OH)Br
Reaction of ethylmagnesium bromide with ethyl acetate in the presence of styrene and titanium(IV) isopropoxide as a catalyst leads to (Z)-1-methyl-2-phenylcyclopropanol in 42% yield.
General DescriptionEthylmagnesium bromide, an organomagnesium compound, is commonly known as Grignard reagent. It is a powerful carbon nucleophile mainly used for C-C bond formation. Ethylmagnesium bromide solution (3.0 M in diethyl ether) can be used for copper(I)-catalyzed allylic substitution reaction.
Grignard reagents are organometallic compounds discovered by a French chemist, Victor Grignard in 1900. These compounds can be obtained as a formula “RMgX” by the reaction of halogenated hydrocarbons with magnesium metal in anhydrous solvents such as diethyl ether,1) and have been widely used in organic synthesis.
HazardFlammable, dangerous fire risk.
Ethylmagnesium bromide Preparation Products And Raw materials
Preparation ProductsTETRAETHYLLEAD-->5-HEXENOIC ACID-->1-Phenyl-1-propanol-->DECANE,3,8-DIMETHYL--->Benzene-13C, 1,2-diethyl- (9CI)-->Phosphine oxide, diethylphenyl--->4-OXO-HEXANOIC ACID-->SEC-BUTYL ETHYL ETHER-->1-ETHYL-1-CYCLOPENTENE-->2,3-Dibromothiophene-->2-Adamantanol-->(1-ETHYLPROPYL)BENZENE-->2-hydroxy-5-(methylthio)benzaldehyde-->2-METHYL-2-PENTANOL-->4-(1-Hydroxy-1-methylpropyl)-2-propyl-1H-Imidazole-5-carboxylic acidethylester-->DIETHYLMETHYLSILANE
ALLYLMAGNESIUM BROMIDE BENZYLMAGNESIUM BROMIDE N-BUTYLMAGNESIUM BROMIDE N-PENTYLMAGNESIUM BROMIDE ISOBUTYLMAGNESIUM BROMIDE 1-METHYL-1-PROPENYLMAGNESIUM BROMIDE N-PROPYLMAGNESIUM BROMIDE ISOPROPYLMAGNESIUM BROMIDE SEC-BUTYLMAGNESIUM BROMIDE 2-BROMOBENZYLMAGNESIUM BROMIDE CYCLOPENTYLMAGNESIUM BROMIDE Cyclopropylmagnesium bromide DECYLMAGNESIUM BROMIDE Ethylmagnesium bromide HEPTYLMAGNESIUM BROMIDE PENTAMETHYLENEBIS(MAGNESIUM BROMIDE) 3,5-DIMETHYLBENZYLMAGNESIUM BROMIDE (1,3-DIOXOLAN-2-YLETHYL)MAGNESIUM BROMIDE

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