MESO-2 3-DIAMINOSUCCINIC ACID

MESO-2 3-DIAMINOSUCCINIC ACID Basic information
Product Name:MESO-2 3-DIAMINOSUCCINIC ACID
Synonyms:erythro-3-aminoaspartic acid;(2R,3S)-diaminosuccinic acid;(2R,3S)-2,3-Diaminosuccinic acid;(3R)-3-Amino-L-aspartic acid;Einecs 245-500-1;D-Aspartic acid, 3-amino-, (3S)-rel-;(2R,3S)-2,3-Diaminosuccinicaci;MESO-2 3-DIAMINOSUCCINIC ACID USP/EP/BP
CAS:23220-52-2
MF:C4H8N2O4
MW:148.12
EINECS:245-500-1
Product Categories:Others;Peptide Synthesis;Unnatural Amino Acid Derivatives;amino
Mol File:23220-52-2.mol
MESO-2 3-DIAMINOSUCCINIC ACID Structure
MESO-2 3-DIAMINOSUCCINIC ACID Chemical Properties
Melting point 304 °C
Boiling point 304.7±42.0 °C(Predicted)
density 1.611±0.06 g/cm3(Predicted)
pka1.43±0.27(Predicted)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
HS Code 29214900
MSDS Information
MESO-2 3-DIAMINOSUCCINIC ACID Usage And Synthesis
Usesmeso-2,3-Diaminosuccinic Acid is used as a building block in organic synthesis. As well as used in the synthesis of metal complexes for antitumor activity.
Purification MethodsCrystallise the acid from water. Also, dissolve it in dilute NaOH and add AcOH to pH 5-6 and allow it to crystallise (m 304o dec). Alternatively dissolve the acid in aqueous NH3 and boil; when the NH3 has evaporated, the acid separates, filter it off and dry it at room temperature in a vacuum. In another procedure 1g of acid is dissolved in 10mL of conc HCl + 15mL of H2O at 80o, filter immediately, dilute with 20mL of H2O and allow to stand for 24hours. When the monohydrochloride (0.7g, m 175-156o dec) crystallises out, filter and dry it. It has also been purified by dissolving it in the minimum volume of 10% HCl, filtering, and diluting with 5volumes of H2O when the crystals separate slowly on standing. The acid is filtered off after 24hours and dried (m 306-306o dec). Similar procedures were used for the dl-isomer. [Kenner J Org Chem 13 28 1948, McKennis & Yard J Org Chem 23 980 1958, Beilstein 4 III 1528, 4 IV 3025.]
MESO-2 3-DIAMINOSUCCINIC ACID Preparation Products And Raw materials
Raw materialserythro-N-benzyl-3-(benzylamino)aspartic acid-->Butanedioic acid, 2,2-dibromo--->Acetic acid
Preparation ProductsDL-2,3-diaminosuccinic acid
Succinic acid DL-α,α'-diaminosuccinic acid

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