4-BOC-1-(5-BROMO-2-PYRIDYL)PIPERAZINE

4-BOC-1-(5-BROMO-2-PYRIDYL)PIPERAZINE Basic information

Product Name:	4-BOC-1-(5-BROMO-2-PYRIDYL)PIPERAZINE
Synonyms:	5-Bromo-2-[4-(N-Boc)piperazin-1-yl]pyridine;1-Piperazinecarboxylic acid, 4-(5-bromo-2-pyridinyl)-, 1,1-dimethylethyl ester;2-(4-BOC-piperazino)-5-bromopyridine;t-Butyl 4-(5-bromopyridin-2-yl)piperazine-1-carboxylate;Palbociclib impurity C;4-Boc-1-(5-bromo-2-pyridyl)piperazine 97%;4-(5-Bromo-pyridin-2-yl)-piperazine-1-carboxylic acid tert-butyl ester;2-(N-Boc-piperazin-1-yl)-5-bromopyridine, tert-Butyl 4-(5μ-bromopyrid-2μ-yl)piperazine-1-carboxylate
CAS:	153747-97-8
MF:	C14H20BrN3O2
MW:	342.23
EINECS:
Product Categories:	Organohalides;Pyridine;piperazines;pharmacetical;alkyl bromide
Mol File:	153747-97-8.mol

4-BOC-1-(5-BROMO-2-PYRIDYL)PIPERAZINE Chemical Properties

Melting point	83-87 °C (lit.)
Boiling point	433.0±45.0 °C(Predicted)
density	1.372±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
form	Powder
pka	6.06±0.29(Predicted)
color	White to yellow
Water Solubility	Soluble in water.

Safety Information

MSDS Information

4-BOC-1-(5-BROMO-2-PYRIDYL)PIPERAZINE Usage And Synthesis

Uses	4-Boc-1-(5-bromo-2-pyridyl)piperazine is used as active pharmaceutical ingredient.

4-BOC-1-(5-BROMO-2-PYRIDYL)PIPERAZINE Preparation Products And Raw materials

Raw materials	8-BOC-3,8-DIAZA-BICYCLO[3.2.1]OCTANE-->5-BROMO-2-(PIPERAZIN-1-YL)PYRIDINE-->2-Fluoro-5-bromopyridine-->2,5-Dibromopyridine-->Di-tert-butyl dicarbonate-->5-Bromo-2-chloropyridine-->tert-Butyl 1-piperazinecarboxylate
Preparation Products	6-(4-N-BOC-PIPERAZINE-1-YL)-3-PYRIDINYL BORONIC ACID-->tert-Butyl 4-(6-chloropyridin-3-yl)piperazine-1-carboxylate-->tert-Butyl 4-(5-hydroxypyridin-2-yl)piperazine-1-carboxylate

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