2-Bromo-3′-hydroxyacetophenone

2-Bromo-3′-hydroxyacetophenone Basic information

Product Name:	2-Bromo-3′-hydroxyacetophenone
Synonyms:	2-bromo-1-(3-hydroxyphenyl)ethan-1-one;2-Bromo-3'-hydroxyacetophenone, 2-Bromo-1-(3-hydroxyphenyl)ethan-1-one, 3-(Bromoacetyl)phenol;M-BroMoacetylphenol;omega-Bromo-m-hydroxyacetophenone;Ethanone,2-broMo-1-(3-hydroxyphenyl)-;Phenylephrine Impurity 64;Carteolol Impurity 13
CAS:	2491-37-4
MF:	C8H7BrO2
MW:	215.04
EINECS:
Product Categories:	Aromatics;Carbonyl Compounds;C7 to C8;Ketones
Mol File:	2491-37-4.mol

2-Bromo-3′-hydroxyacetophenone Chemical Properties

Melting point	70-74 °C(lit.)
Boiling point	327.8±22.0 °C(Predicted)
density	1.622±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	soluble in Dichloromethane, Ethyl Acetate, Methanol
form	powder
pka	8.97±0.10(Predicted)
color	Fawn to brown

Safety Information

MSDS Information

2-Bromo-3′-hydroxyacetophenone Usage And Synthesis

Chemical Properties

White Solid

Uses

Reactant involved in the synthesis of:

Pyrrole-3-carboxylic acids
N-aryl-N-thiazolyl compounds via the Hantzsch reaction
Disubstituted oxadiazolylindole derivatives with antiinflammatory, analgesic and nitric oxide releasing activity
Anilino-aryl-thiazoles with inhibitory activity toward valosin-containing proteins
Tyrosine kinase erythropoietin inhibitors
E. coli methionine aminopeptidase inhibitors

2-Bromo-3′-hydroxyacetophenone Preparation Products And Raw materials

Raw materials	Ethanone, 1-[3-(1,1-dimethylethoxy)phenyl]--->Phenol, 3-(2-bromoethynyl)--->2-BROMO-3'-ACETYLOXYLACETOPHENONE-->3'-METHOXYPHENACYL BROMIDE-->3'-Acetoxyacetophenone-->3'-Hydroxyacetophenone
Preparation Products	1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride-->norfenefrine

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