2-Amino-5-fluoropyridine

2-Amino-5-fluoropyridine Basic information

Product Name:	2-Amino-5-fluoropyridine
Synonyms:	5-FLUORO-2-PYRIDINAMINE;5-FLUOROPYRIDIN-2-AMINE;5-FLUORO-PYRIDIN-2-YL-AMINE;5-FLUORO-2-AMINOPYRIDINE;2-Amino-5-fluoroypyridine;2-Amino-5-fluoropyridine 95%;2-Amino-5-fluoropyridine95%;2-AMINO-5-FLUOROPYRIDINE, 98+%
CAS:	21717-96-4
MF:	C5H5FN2
MW:	112.11
EINECS:	627-638-8
Product Categories:	Boronic Acid;C5;blocks;Heterocyclic Building Blocks;Amino-pyridine series;Fluorine series;Fluorin-contained pyridine series;FluoroCompounds;Heterocycles;Pyridines;Pyridine;Pyridine series;Pyridines derivates;Fluoropyridines;Halopyridines
Mol File:	21717-96-4.mol

2-Amino-5-fluoropyridine Chemical Properties

Melting point	93-97 °C (lit.)
Boiling point	125 °C
density	1.257±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	soluble in Methanol
pka	4.62±0.13(Predicted)
form	Powder
color	White to orange
BRN	385938
InChI	InChI=1S/C5H5FN2/c6-4-1-2-5(7)8-3-4/h1-3H,(H2,7,8)
InChIKey	YJTXQLYMECWULH-UHFFFAOYSA-N
SMILES	C1(N)=NC=C(F)C=C1
CAS DataBase Reference	21717-96-4(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi,C
Risk Statements	36/37/38-34
Safety Statements	26-36-45-36/37/39-27
RIDADR	UN2811
WGK Germany	3
Hazard Note	Irritant
HazardClass	6.1
PackingGroup	II
HS Code	29333999

MSDS Information

Provider	Language
SigmaAldrich	English
ALFA	English

2-Amino-5-fluoropyridine Usage And Synthesis

Chemical Properties	Light yellow Cryst
Uses	2-Amino-5-fluoropyridine is used in chemical microarrays to identify ligands that binds pathogenic cells. Acts as a reagent in the preparation of heterocyclic compounds as integrase inhibiting antiviral agents.
Definition	ChEBI: 2-Amino-5-fluoropyridine is a dihydropyridine.
Synthesis	2-Amino-5-fluoropyridine is an important intermediate for the synthesis of LBM415 which is the peptide deformylas inhibitor. Using 2-aminopyridine as raw material and via nitrification, amino acetylation, reduction of nitro, diazolization, Schiemann reaction and hydrolysis of acetyl.

2-Amino-5-fluoropyridine Preparation Products And Raw materials

Raw materials	Ethanol-->Acetic anhydride-->Benzene-->Palladium-->Xylene-->Fluoroboric acid-->Isoamyl nitrite-->2-Amino-5-nitropyridine
Preparation Products	5-Amino-2-chloropyridine-->2-Bromo-5-fluoropyridine-->5-Fluoro-2-nitropyridine-->2-Cyano-5-fluoropyridine-->Imidazo[1,2-a]pyridine, 6-fluoro- (9CI)-->(5-Fluoro-pyridin-2-yl)-Methyl-aMine-->ETHYL 6-FLUORO-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLATE

Alatrofloxacin 2-Fluoropyridine ALTRENOGEST Esafloxacin 1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-6-fluoro-1-(2-fluoroe thyl)-4-oxo-7-(1-piperazinyl)- 6-Fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1-vinyl-1,8-naphthyridine -3-carboxylic acid 3-Aminopyridine 6-Aminocaproic acid Glycine 2,6-DITERT-BUTYL-4-(2,3,5-TRIFLUORO-6-(4-METHYLPIPERAZIN-1-YL)PYRIDIN-4-YLTHIO)PHENOL Flupirtine 2-Aminopyridine Tris(hydroxymethyl)aminomethane 2-Amino-5-fluoropyridine AMINO ACIDS 3-Aminophenol 3-Aminobenzotrifluoride 4-Dimethylaminopyridine

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