ChemicalBook Product Catalog Biochemical Engineering Amino Acids and proteins D(-)-Norvaline

D(-)-Norvaline

D(-)-Norvaline Basic information
Product Name:D(-)-Norvaline
Synonyms:H-D-NVA-OH;H-D-NHCH[CH3(CH2)2]-COOH;H-D-NORVALINE;H-D-APE(2)-OH;D-NVal-OH;H-D-2-AMINOVALERIC ACID;D-Nva-OH;D-Nval
CAS:2013-12-9
MF:C5H11NO2
MW:117.15
EINECS:217-936-2
Product Categories:Amino Acids;Peptide;Norvaline [Nva];bc0001
Mol File:2013-12-9.mol
D(-)-Norvaline Structure
D(-)-Norvaline Chemical Properties
Melting point >300 °C(lit.)
alpha -24 º (c=5, 5N HCl)
Boiling point 222.9±23.0 °C(Predicted)
density 1.2000 (estimate)
refractive index -25 ° (C=10, 6mol/L HCl)
storage temp. Store at RT.
solubility Aqueous Acid (Slightly), Water (Slightly)
form Solid
pka2.54±0.20(Predicted)
color White to Off-White
optical activity[α]20/D 24°, c = 10 in 5 M HCl
Water Solubility SOLUBLE
Merck 14,6716
BRN 1721161
CAS DataBase Reference2013-12-9(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 20/21/22-36/37/38
Safety Statements 22-24/25-37/39-26
WGK Germany 3
HS Code 29224919
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
D(-)-Norvaline Usage And Synthesis
Chemical Propertieswhite to off-white crystals or crystalline powder
UsesD-Norvaline is used as a catalyst in the enantioselective α-bromination of carbonyl and 1,3-dicarbonyl compounds. D-Norvaline is also incorporated into jadomycins (a group of compounds that are widely used as antibiotics), ultimately producing compounds that have potential antiproliferative/anti-cancer properties.
DefinitionChEBI: D-2-aminopentanoic acid is a 2-aminopentanoic acid that has R-configuration. It has a role as an EC 6.1.1.4 (leucine--tRNA ligase) inhibitor. It is a D-alpha-amino acid and a 2-aminopentanoic acid. It is an enantiomer of a L-2-aminopentanoic acid.
D(-)-Norvaline Preparation Products And Raw materials
Raw materials2-Amino-pentanoic acid benzyl ester-->DL-Norvaline-->2-Amino-pentanamide HCl-->L-Norvaline
Preparation ProductsD(-)-Glutamic acid
Estradiol valerate MAGNESIUM DIPROPYLACETATE HYDRATE DL-NORVALINE SIGMA GRADE,DL-NORVALINE 98% Ascoric Acid Pivalic acid Z-PRO-D-LEU-OH D-Lysine hydrochloride Valine cis-4-Hydroxy-D-proline D-Norleucine Ethyl D-(-)-pyroglutamate D-Lysine BOC-D-Arg(Tos)-OH 2-Propylpentanoic acid L-Norvaline D(-)-Norvaline 5-AMINOVALERIC ACID Citric acid
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