Glycoluril

Glycoluril Basic information
Product Name:Glycoluril
Synonyms:5-d]imidazole-2,5(1h,3h)-dione,tetrahydro-imidazo[;5-d]imidazole-2,5(1H,3H)-dione,tetrahydro-Imidazo[4;Acetylenediureine;Diurea glyoxalate;Glyoxalbiuret;Glyoxaldiureine;Glyoxaldiurene;Imidazo[4,5-d]imidazole-2,5(1H,3H)-dione, tetrahydro-
CAS:496-46-8
MF:C4H6N4O2
MW:142.12
EINECS:207-821-5
Product Categories:Heterocyclic Compounds;Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks;N-Containing;Others
Mol File:496-46-8.mol
Glycoluril Structure
Glycoluril Chemical Properties
Melting point >300 °C (lit.)
Boiling point 259.66°C (rough estimate)
density 1.4926 (rough estimate)
vapor pressure 0Pa at 25℃
refractive index 1.8500 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility 15g/l
pka12.91±0.20(Predicted)
form powder to crystal
color White to Almost white
Water Solubility 1.8g/L at 20℃
Merck 14,93
BRN 128826
LogP-3.28
CAS DataBase Reference496-46-8(CAS DataBase Reference)
NIST Chemistry ReferenceGlycoluril(496-46-8)
EPA Substance Registry SystemGlycoluril (496-46-8)
Safety Information
Hazard Codes Xn
Risk Statements 22
Safety Statements 24/25
WGK Germany 1
HS Code 29332990
MSDS Information
ProviderLanguage
Acetylenediurea English
SigmaAldrich English
ACROS English
Glycoluril Usage And Synthesis
Chemical PropertiesWHITE TO VERY SLIGHTLY YELLOW CRYSTALLINE POWDER
UsesReactant involved in synthesis of:• ;Glycouril hexamers and monofunctionalized cucurbit[6]uril derivatives1,2,3• ;N-chloro compounds from trichloroisocyanuric acid4• ;Glycouril trimers5
UsesGlycoluril is used as a reagent in the synthesis of acyclic cucurbit[n]uril molecular containers which can enhance the solubility and bioactivity of poorly soluble pharmaceuticals. Also used as a reagent in the synthesis of cucurbit[7]uril containers for targeted delivery of oxaliplatin to cancer cells.
UsesFor derivatives glycoluril, glycoluril resins
DefinitionChEBI: Glycoluril is an azabicycloalkane and a member of ureas.
Flammability and ExplosibilityNotclassified
Agricultural UsesGlycine is the simplest naturally occurring amino acid and is a constituent of most proteins. Its formula is H2N·CH2·COOH.
Glycoluril Preparation Products And Raw materials
Preparation ProductsCUCURBIT(7)URIL-->PARABANIC ACID-->CUCURBITURIL
3-(2,5-DIOXO-HEXAHYDRO-IMIDAZO[4,5-D]IMIDAZOL-1-YL)-PROPIONIC ACID 1,3,4,6-TETRACHLORO-3ALPHA,6ALPHA-DI-PHENYLGLYCOURIL [2-(2,5-DIOXO-HEXAHYDRO-IMIDAZO[4,5-D]IMIDAZOL-1-YL)-ACETYLAMINO]-ACETIC ACID 1,4-diacetyltetrahydroimidazo[4,5-d]imidazole-2,5(1H,3H)-dione CUCURBITURIL 1,3,4,6-Tetrakis(methoxymethyl)glycoluril 2-(2,5-DIOXO-HEXAHYDRO-IMIDAZO[4,5-D]IMIDAZOL-1-YL)-4-METHYLSULFANYL-BUTYRIC ACID N,N',N'',N'''-TETRACHLOROGLYCOLURIL SPECS AA-516/25012248 4-(2,5-DIOXO-HEXAHYDRO-IMIDAZO[4,5-D]IMIDAZOL-1-YL)-BUTYRIC ACID N,N',N'',N'''-Tetraacetylglycoluril HEXAHYDRO-2,6-BIS(2,2,6,6-TETRAMETHYL-4-PIPERIDINYL)-1H,4H,5H,8H-2,3A,4A,6,7A,8A-HEXAAZACYCLOPENTA[DEF]FLUORENE-4,8-DIONE (4,6-DIMETHYL-2,5-DIOXO-HEXAHYDRO-IMIDAZO-[4,5-D]IMIDAZOL-1-YL)-ACETIC ACID 3a,6a-Diphenyloctahydroimidazo[4,5-d]imidazole-2,5-dione (2,5-DIOXO-HEXAHYDRO-IMIDAZO[4,5-D]-IMIDAZOL-1-YL)-ACETIC ACID 2-(2,5-DIOXOHEXAHYDROIMIDAZO[4,5-D]IMIDAZOL-1(2H)-YL)BUTANOIC ACID 3-(4,6-DIMETHYL-2,5-DIOXOHEXAHYDROIMIDAZO[4,5-D]IMIDAZOL-1(2H)-YL)PROPANOIC ACID 1,3,4,6-TETRAKIS(BUTOXYMETHYL)GLYCOLURIL, TECH.

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