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| | FENPICLONIL Basic information |
| | FENPICLONIL Chemical Properties |
| Melting point | 152.9℃ | | Boiling point | 378.43°C (rough estimate) | | density | 1.4052 (rough estimate) | | vapor pressure | 1.1 x 10-7 Pa (25 °C) | | refractive index | 1.6400 (estimate) | | Water Solubility | 4.8 mg l-1 in water at 25 °C | | form | neat | | pka | 13.63±0.50(Predicted) | | Merck | 13,4016 | | BRN | 5433281 | | EPA Substance Registry System | 1H-Pyrrole-3-carbonitrile, 4-(2,3-dichlorophenyl)- (74738-17-3) |
| Hazard Codes | Xn | | Risk Statements | 20 | | RIDADR | 3077 | | WGK Germany | 2 | | RTECS | UX9347500 | | HazardClass | 9 | | PackingGroup | III | | Toxicity | LD50 in rats, mice, rabbits (mg/kg): >5000 orally; LD50 dermally in rats: >2000 mg/kg; LC50 (4 hr) in rats: >1502 mg/m3 by inhalation (Nevill) |
| | FENPICLONIL Usage And Synthesis |
| Description | Fenpiclonil is the
first phenylpyrrole fungicide developed by Ciba Geigy
(now belonging to the portfolio of Syngenta Crop Protection
AG) for seed treatment. Different formulation
types have been used for its commercialization either
in solo (trade name “Beret”) or in mixture with other
fungicides, as for instance, imazalil (“Beret Special”) or
carboxin + imazalil (“Beret Universal”). | | Uses | Agricultural fungicide. | | Uses | Fenpiclonil is a systemic and contact fungicide that provides protective
control of seed-borne pathogens of cereals such as snow mould
and bunt caused by Fusarium spp., Tilletia caries, Septoria nodorum, etc. It
also controls leaf spot, brown foot rot and ear blight in non-cereal crops. | | Definition | ChEBI: A member of the class of pyrroles carrying cyano and 2,3-dichlorophenyl substituents at positions 3 and 4 respectively. A fungicide used mainly to control seed-borne pathogens in cereal crops. | | General Description | Fenpiclonil is a phenylpyrrole fungicide and a structural analogue of the antibiotic pyrrolnitrin found to be toxic to representatives of Ascomycetes, Basidiomycetes, and Deuteromycetes. | | Metabolic pathway | Limited data are available in the open literature. Information presented in
this summary was abstracted from the data evaluation published by the
Pesticide Safety Directorate (PSD, 1993). Fenpiclonil is stable to hydrolytic
and soil degradation. Photolytic degradation is rapid. Hydroxylation
and oxidation of the pyrrole ring are the primary metabolic reactions in
plants and animals (Scheme 1). | | Degradation | Fenpiclonil (1) is stable to hydrolytic degradation (up to 70 °C) over the
pH range 5-9.
Fenpiclonil degraded rapidly in water (pH 7) when samples were
irradiated under a mercury arc lamp (>290 nm) with an estimated DT50
values of <1 hour. At least eight unidentified degradation products were
observed |
| | FENPICLONIL Preparation Products And Raw materials |
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