N-Methyl-1-(methylthio)-2-nitroethylen-1-amine

N-Methyl-1-(methylthio)-2-nitroethylen-1-amine Basic information
Product Name:N-Methyl-1-(methylthio)-2-nitroethylen-1-amine
Synonyms:1-METHYLAMINO-1-METHYLTHIO-2-NITROETHYLENE;1-METHYLAMINO-1-METHYLTHIONITRO ETHENE;1-METHYLAMINO-1-METHYTHIO-2-NITROETHYLENE;1-METHYL-1-METHYLTHIO-2-NITROETHENAMINE;N-Methyl-1-(methylth;1-(Methylthio)-2-nitro-N-MethylethyleneaMine;2-(Methylthio)-2-(MethylaMino)-1-nitroethene;Nizatidine EP IMpurity B
CAS:61832-41-5
MF:C4H8N2O2S
MW:148.18
EINECS:263-266-9
Product Categories:Intermediates;Sulfur & Selenium Compounds;Sulfur Compounds;Amines;(intermediate of ranitidine);PHARMACEUTICAL INTERMEDIATES;Anilines, Aromatic Amines and Nitro Compounds;Organic Building Blocks;Sulfides/Disulfides
Mol File:61832-41-5.mol
N-Methyl-1-(methylthio)-2-nitroethylen-1-amine Structure
N-Methyl-1-(methylthio)-2-nitroethylen-1-amine Chemical Properties
Melting point 112-118 °C (lit.)
Boiling point 236.5±35.0 °C(Predicted)
density 1.199±0.06 g/cm3(Predicted)
solubility Chloroform, Methanol (Sparingly)
pka0.86±0.70(Predicted)
form powder to crystal
color Light orange to Yellow to Green
BRN 2828017
CAS DataBase Reference61832-41-5(CAS DataBase Reference)
NIST Chemistry ReferenceEthenamine, n-methyl-1-(methylthio)-2-nitro-(61832-41-5)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37/39
RIDADR UN 3335
WGK Germany 3
Hazard Note Irritant
HS Code 29309090
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
N-Methyl-1-(methylthio)-2-nitroethylen-1-amine Usage And Synthesis
Chemical PropertiesYellow Solid
UsesIntermediate in the preparation of Ranitidine and Nizatidine.
Uses(E) N-methyl-1-(methylthio)-2-nitroethenamine) (NMSM) may be used for the following syntheses:
  • pyrano[2,3-c]pyrazol-6-amines
  • 6-methoxy-N-methyl-3-nitro-4-nitromethyl-4H-chromen-2-amine
N-Methyl-1-(methylthio)-2-nitroethylen-1-amine Preparation Products And Raw materials
Raw materialsPotassium hydroxide-->Dimethyl sulfate-->Xylene-->Carbon disulfide-->Nitromethane
Preparation ProductsRanitidine
nitrotoluene Methyl 5-[(3-METHOXYPHENYL)METHYLENE]-3-METHYL-2-(NITROMETHYLENE)-1,3-THIAZOLAN-4-ONE 2-NITROMETHYLENETHIAZOLIDINE 5-[(3-CHLOROPHENYL)METHYLENE]-3-METHYL-2-(NITROMETHYLENE)-1,3-THIAZOLAN-4-ONE 5-[(2-HYDROXYPHENYL)METHYLENE]-3-METHYL-2-(NITROMETHYLENE)-1,3-THIAZOLAN-4-ONE 1-(4-([1-(METHYLSULFANYL)-2-NITROVINYL]AMINO)PHENYL)-1-ETHANONE 2-ETHOXY-N-[1-(METHYLSULFANYL)-2-NITROVINYL]ANILINE 5-[(DIMETHYLAMINO)METHYLENE]-3-METHYL-2-(NITROMETHYLENE)-1,3-THIAZOLAN-4-ONE 3-METHYL-2-(NITROMETHYLENE)-1,3-THIAZOLAN-4-ONE ISOMETHIOZIN 6-BENZYLAMINO-5-NITROIMIDAZO-(2,1-B)-THIAZOLE N-[1-(METHYLSULFANYL)-2-NITROVINYL]-N-PHENYLAMINE Silicone rubber,methyl-vinyl 4-methoxy-N-[1-(methylsulfanyl)-2-nitrovinyl]aniline 4-CHLORO-N-[1-(METHYLSULFANYL)-2-NITROVINYL]ANILINE METHYL THIOPHENE-2-CARBOXYLATE N,1-DIMETHYL-6-(METHYLSULFANYL)-3,5-DINITRO-1,4-DIHYDRO-2-PYRIDINAMINE

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