Hexyl nicotinate

Hexyl nicotinate Basic information
Product Name:Hexyl nicotinate
Synonyms:3-Pyridinecarboxylic acid, hexyl ester;3-pyridinecarboxylicacid,hexylester;Nicotherm;N-HEXYL NICOTINATE;n-Hexyl nicotinoate;NICOTINIC ACID N-HEXYL ESTER;NICOTINIC ACID HEXYL ESTER;HEXYL PYRIDINE-3-CARBOXYLATE
CAS:23597-82-2
MF:C12H17NO2
MW:207.27
EINECS:245-767-4
Product Categories:
Mol File:23597-82-2.mol
Hexyl nicotinate Structure
Hexyl nicotinate Chemical Properties
Boiling point 140°C
density 1,02 g/cm3
refractive index 1.4880 to 1.4920
storage temp. Inert atmosphere,Room Temperature
pka3.21±0.10(Predicted)
form clear liquid
color Colorless to Almost colorless
Water Solubility 0.17g/L(32 ºC)
LogP3.510
CAS DataBase Reference23597-82-2(CAS DataBase Reference)
NIST Chemistry Reference3-Pyridinecarboxylic acid, hexyl ester(23597-82-2)
EPA Substance Registry SystemHexyl nicotinoate (23597-82-2)
Safety Information
Risk Statements 36/37/38
Safety Statements 26-36/37/39
HS Code 29333990
MSDS Information
Hexyl nicotinate Usage And Synthesis
DescriptionHexyl Nicotinate is an active substance from the group of rubefacients that stimulates blood circulation. It is used for topical treatment of muscle, joint and ligament pain. Hexyl Nicotinate can be used in creams, baths and emulsions, in veterinary as well as in human medicines.
Useshexyl nicotinate penetrates rapidly and dilates blood vessels, thereby temporarily activating blood circulation. This increased blood flow results in an enhanced supply of oxygen, nutrients, and moisture to the skin cells, along with a faster elimination of wastes by means of the metabolic process.
UsesHexyl Nicotinoate is a nicotinic acid ester prodrug.
ApplicationHexyl Nicotinate is used as a cosmetic ingredient in several applications such as Sun tanning lotion, creams, slimming gels, and creams. It is preferred over Niacin due to its better penetrating power.
1.Used in hair loss creams and lotions as vasodilator.
2.Ingradient of Transvasin heat rub cream. (Thornton & Ross)
3.Used in almost all slimming and tanning cosmetic formulations.
benefits1. Preferred over Niacin due to its better penetrating power.
2. Hexyl Nicotinate demonstrates better rubefacient properties which can produce pronounced thermo-slimming compositions.
3. Hexyl Nicotinate enhances blood circulation in the skin and enhances the skin's metabolism.
Hexyl nicotinate Preparation Products And Raw materials
Raw materialsNicotinoyl chloride hydrochloride-->1-Hexanol-->3,4-Pyridinedicarboxylic acid-->Nicotinic acid
Ethylhexyl Palmitate Nicomol 5-bromo-3-(10-methoxy-1,6-dimethylergolin-8beta-ylmethoxycarbonyl)pyridinium hydrogen [R-(R*,R*)]-tartrate 3-Pyridinecarboxylic acid, 6-(4-((4-chlorophenyl)methoxy)phenyl)hexyl ester NICOTINIC ACID N-OCTYL ESTER Inositol nicotinate WILFORGINE Hepronicate wilfortrine Vitamin E nicotinate MENTHYL NICOTINATE sorbinicate POLY(1 6-HEXAMETHYLENE ADIPATE) AVERAG& Nicotinic acid, 2,11-dibutyl-2,11-dimethyldodecamethylene ester DI-N-HEXYL PHTHALATE Hoechst 33258 VITAMIN E NICOTINATE Hexyl nicotinate

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