Ethyl 2-hydroxyisobutyrate

Ethyl 2-hydroxyisobutyrate Basic information

Product Name:	Ethyl 2-hydroxyisobutyrate
Synonyms:	ETHYL 2-HYDROXY-2-METHYLPROPIONATE;Ethyl hydroxyisobutyrate;ETHYL-ALPHA-HYDROXY-ISO-BUTYRATE;2-HYDROXYISOBUTYRIC ACID ETHYL ESTER;2-METHYLLACTIC ACID ETHYL ESTER;Methyllactic acid ethyl ester, 2-: (Ethyl 2-hydroxyisobutyrate);Ethyl alpha-hydroxyisobutyrate 98%;Ethyl 2-hydroxy-2-methylpropionate 2-Hydroxyisobutyric Acid Ethyl Ester
CAS:	80-55-7
MF:	C6H12O3
MW:	132.16
EINECS:	201-290-3
Product Categories:	Building Blocks;C6 to C7;Carbonyl Compounds;Chemical Synthesis;Esters;Organic Building Blocks;Miscellaneous
Mol File:	80-55-7.mol

Ethyl 2-hydroxyisobutyrate Chemical Properties

Melting point	78 °C
Boiling point	150 °C (lit.)
density	0.965 g/mL at 25 °C (lit.)
refractive index	n20/D 1.408(lit.)
Fp	112 °F
storage temp.	Flammables area
pka	13.28±0.29(Predicted)
form	clear liquid
color	Colorless to Almost colorless
BRN	878308
CAS DataBase Reference	80-55-7(CAS DataBase Reference)
NIST Chemistry Reference	Propanoic acid, 2-hydroxy-2-methyl-, ethyl ester(80-55-7)
EPA Substance Registry System	Propanoic acid, 2-hydroxy-2-methyl-, ethyl ester (80-55-7)

Safety Information

Hazard Codes	Xi
Risk Statements	10-36/37/38-36/38
Safety Statements	26-36-16
RIDADR	UN 3272 3/PG 3
WGK Germany	3
RTECS	OD5672000
HazardClass	3
PackingGroup	III
HS Code	29181980

MSDS Information

Provider	Language
Ethyl alpha-hydroxyisobutyrate	English
SigmaAldrich	English
ACROS	English
ALFA	English

Ethyl 2-hydroxyisobutyrate Usage And Synthesis

Chemical Properties	clear colorless liquid
Uses	Solvent for nitrocellulose and cellulose acetate; solvent mixture for cellulose ethers, organic synthesis, pharmaceuticals.

Ethyl 2-hydroxyisobutyrate Preparation Products And Raw materials

Raw materials	2-Amino-2-methyl-propionic acid ethyl ester hydrochloride-->2-Hydroxyisobutyric acid-->Acetone cyanohydrin-->Ethanol-->Diethyl oxalate-->Hydrochloric acid-->Ethyl 2-bromoisobutyrate-->Formaldehyde-->Iodoethane-->Ethyl oxalyl monochloride
Preparation Products	10-METHYLACRIDINIUM PERCHLORATE-->3,5,5-TRIMETHYLOXAZOLIDINE-2,4-DIONE-->Methacrylic acid-->α-Hydroxyisobutyric acid butyl ester

HYDROXYAPATITE TYPE I L(+)-Lactic acid Ethyl 3-hydroxybutyrate 2,2-Bis(hydroxymethyl)propionic acid Hydroxy silicone oil Isobutyric acid 2-Hydroxyethyl methacrylate CHLOROETHANE Methyl 2-hydroxyisobutyrate Diethyl methylmalonate Cumyl hydroperoxide 2-Hydroxypyridine Ethyl isobutyrate Triethyl orthopropionate CHLOROPHOSPHONAZO III Ethyl S-4-chloro-3-hydroxybutyrate Glycolic acid Phenoxyethyl isobutyrate

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