ChemicalBook Product Catalog API Circulatory system drugs Antihypertensive drugs 5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole Basic information
Product Name:5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole
Synonyms:N-(Triphenylmethyl)-5-(4'-bromomethylbiphenyl-2-yl-)terazole;N-(TRIPHENYLMETHYL)-5-(4'-BROMOMETHYLBIPHENYL-2-YL) TETRAZOLE;5-(4'-BROMOMETHYL-1,1'-BIPHENYL-2-YL)-1-TRIPHENYLMETHYL-1H-TETRAZOLE;5-(4'-BROMOMETHYL-BIPHENYL-2-YL)-1-TRITYL-1H-TETRAZOLE;1H-Tetrazole, 5-[4'-(bromomethyl)[1,1'-biphenyl]-2-yl]-1-(triphenylmethyl)-;Trityl tetrazole bromomethyl biphenyl;5-(4'-(BROMOMETHYL)(1,1'-BIPHENYL)-2-YL)-1-TRITYL-;5-[4'-(Bromomethyl)[1,1'-Biphenyl]-1-(Triphenylmethyl)Tetrazole]
CAS:124750-51-2
MF:C33H25BrN4
MW:557.48
EINECS:603-010-9
Product Categories:Amines;Aromatics;Heterocycles;Intermediates;Hypertension;(intermediates of candesartan cilexetil);API intermediates;Tetrazoles;INTERMEDIATESOF;Biphenyl & Diphenyl ether;1
Mol File:124750-51-2.mol
5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole Structure
5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole Chemical Properties
Melting point 152-155°C
Boiling point 61°C/12mmHg(lit.)
density 1.28±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,2-8°C
pka0.29±0.10(Predicted)
Stability:Moisture Sensitive
InChIInChI=1S/C33H25BrN4/c34-24-25-20-22-26(23-21-25)30-18-10-11-19-31(30)32-35-36-37-38(32)33(27-12-4-1-5-13-27,28-14-6-2-7-15-28)29-16-8-3-9-17-29/h1-23H,24H2
InChIKeyZTFVTXDWDFIQEU-UHFFFAOYSA-N
SMILESN1(C(C2=CC=CC=C2)(C2=CC=CC=C2)C2=CC=CC=C2)C(C2=CC=CC=C2C2=CC=C(CBr)C=C2)=NN=N1
CAS DataBase Reference124750-51-2(CAS DataBase Reference)
Safety Information
RIDADR UN 2811 6.1/PG III
HazardClass 6.1
PackingGroup III
MSDS Information
5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole Usage And Synthesis
Chemical PropertiesOff-White Solid
UsesAn intermediate in the synthesis of Losartan and Valsartan
5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole Preparation Products And Raw materials
Preparation ProductsTrityl olmesartan-->Ethyl-2-Ethoxy-1-[[(2'-(1h-Tetrazol-5-Yl)Biphenyl-4-Yl)Methyl]Benzimidazole]-7-Carboxylate-->1H-IMidazole-5-carboxylic acid, 4-(1-hydroxy-1-Methylethyl)-2-propyl-1-[[2'-[1-(triphenylMethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]Methyl]-, ethyl ester-->1H-Imidazole-4,5-dicarbonitrile, 2-butyl-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]--->diethyl 2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-4,5-dicarboxylate-->2-Butyl-4-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxaldehyde
4-(1-Methoxy-1-methylethyl)-2-propyl-1H-Imidazole-5-carboxylic acid ethyl ester 2-(2-butyl-4-hydroxy-6-MethylpyriMidin-5-yl)-N,N-diMethylacetaMide OlMesartan MedoxoMil Methyl Ether IMpurity N-Trityl Olmesartan Ethyl Ester OlMesartan MedoxoMil iMpurity V Olmesartan Impurity 19 Diethyl 2-propylImidazoledicarbonate 2-Butyl-1,6-dihydro-N,N,4-trimethyl-6-oxo-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-5-pyrimidineacetamide OlMesartan MedoxoMil Butyl IMpurity 5-[4'-(Bromomethyl)-[1,1'-biphenyl]-2-yl]-2-(triphenylmethyl)-2H-tetrazole 2-(1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)-2-butyl-4-Methyl-6-oxo-1,6-dihydropyriMidin-5-yl) -N,N-diMethylacetaMide METHYL TRIPHENYLMETHYL ETHER 2-(2-butyl-4-Methyl-6-oxo-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)-1,6-dihydropyriMidin-5-yl)-N,N-diMethylethanethioaMide 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole 5-BIPHENYL-2-YL-2H-TETRAZOLE 2-Bromobiphenyl 5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole 5-[2-(4'-METHYLBIPHENYL)]TETRAZOLE
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