4-Methoxypyridine

4-Methoxypyridine Basic information
Product Name:4-Methoxypyridine
Synonyms:gamma-Methoxypyridine;4-METHOXYPYRIDINE;METHYL PYRIDIN-4-YL ETHER;4-METHOXYPYRIDINE, 98+%;4-methoxypridine;Pyridine, 4-methoxy-;4-Methoxypyridine, 99% 5ML;4-Methoxypyridine,99%
CAS:620-08-6
MF:C6H7NO
MW:109.13
EINECS:210-624-7
Product Categories:C6;Heterocyclic Building Blocks;Pyridines, Pyrimidines, Purines and Pteredines;Pyridine series;Pyridine Derivertives;Boronic Acid;blocks;Pyridines;Pyridine
Mol File:620-08-6.mol
4-Methoxypyridine Structure
4-Methoxypyridine Chemical Properties
Melting point 4 °C
Boiling point 108-111 °C/65 mmHg (lit.)
density 1.075 g/mL at 25 °C (lit.)
refractive index 1.518-1.522
Fp 74 °C
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Liquid
pka6.58(at 25℃)
Specific Gravity1.075
color Clear colorless to slightly yellow
BRN 108211
CAS DataBase Reference620-08-6(CAS DataBase Reference)
NIST Chemistry ReferencePyridine, 4-methoxy-(620-08-6)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 36/37/38-20/21/22
Safety Statements 37/39-26-36-36/37/39
WGK Germany 3
HS Code 29339900
MSDS Information
ProviderLanguage
ACROS English
ALFA English
4-Methoxypyridine Usage And Synthesis
Chemical Propertiesclear colorless to slightly yellow liquid
Uses4-Methoxypyridine, is used as a building block for the synthesis of some biologically active compounds. It is used for the preparation of a new series of benzoylated N-ylides as protein farnesyltransferase inhibitors.
Uses4-Methoxypyridine was used as a starting reagent for the stereocontrolled synthesis of (±)-pumiliotoxin C and (±)-lasubine II. It was also used in an efficient construction of dihyropyridin-4-ones, which serves as potential ligands for neuronal nicotinic acetycholine receptors.
General Description4-Methoxypyridine has been prepared from 4-methoxypyridine-N-oxide, via catalytic hydrogenation. Ortho lithiation of 4-methoxypyridine using mesityllithium as the metalating base has been studied.
4-Methoxypyridine Preparation Products And Raw materials
Preparation Products4-N-DECYLPYRIDINE-->3,4-Dimethoxy-2-Methylpyridine-->4-Methoxypiperidine-->3-BROMO-4-METHOXY-PYRIDINE-->2-Bromo-4-methoxypyridine-->4-Methoxypyridine N-oxide-->BENZYL 2-N-PROPYL-4-OXO-3,4-DIHYDROPYRIDINE-1(2H)-CARBOXYLATE-->benzyl 3,4-dihydro-4-oxo-2-phenylpyridine-1(2H)-carboxylate-->PHENYL 4-OXO-2-PHENYL-3,4-DIHYDROPYRIDINE-1(2H)-CARBOXYLATE-->3-Pyridinecarboxaldehyde, 4-methoxy-5-methyl- (9CI)
4-Methoxy-3-nitropyridine 1,3-DIMETHYL-4-METHOXYPYRAZOLO[3,4-B]PYRIDINE-5-CARBOXYLIC ACID ETHYL 4-(3,5-DICHLOROPHENOXY)-1,3-DIMETHYL-1H-PYRAZOLO[3,4-B]PYRIDINE-5-CARBOXYLATE 4-METHOXYPYRIDINE-N-OXIDE HYDRATE, 99 CORYSAMINE CHLORIDE 4-Methoxybenzylchloride 2-Methoxypyridine 4-Methylpyridine 4-Methoxyphenylacetone Anisole 4-Methoxyphenylacetic acid 4-(Benzyloxy)pyridine N-oxide (Trifluoromethoxy)benzene 3-(METHOXYMETHOXY)BENZALDEHYDE ETHYL 4-(4-METHOXYPHENOXY)-1,3-DIMETHYL-1H-PYRAZOLO[3,4-B]PYRIDINE-5-CARBOXYLATE p-Anisidine p-Anisaldehyde 4-Methoxypyridine

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