1-Benzylpiperazine

1-Benzylpiperazine Basic information

Product Name:	1-Benzylpiperazine
Synonyms:	TIMTEC-BB SBB007534;4-BENZYLPIPERAZINE;N-BENZYLPIPERAZINE;N-(PHENYLMETHYL)PIPERAZINE;1-BENZYLPIPERAZINE 98%;N-Benylpiperazine;1-Benzylpiperazine, 98+%;N-(Phenylmethyl)Piperaine
CAS:	2759-28-6
MF:	C11H16N2
MW:	176.26
EINECS:	220-423-6
Product Categories:	PHARMACEUTICAL INTERMEDIATES;Building Blocks;BA - BHBuilding Blocks;Alphabetic;B;Heterocyclic Building Blocks;PIPERIDINE;pharmacetical;Piperaizine;Piperazines;pharmaceutical intermediate
Mol File:	2759-28-6.mol

1-Benzylpiperazine Chemical Properties

Melting point	17-20 °C
Boiling point	143-146/12mm
density	1.014 g/mL at 25 °C(lit.)
refractive index	n20/D 1.547(lit.)
Fp	>230 °F
pka	9.25±0.10(Predicted)
CAS DataBase Reference	2759-28-6(CAS DataBase Reference)
NIST Chemistry Reference	1-Benzylpiperazine(2759-28-6)
EPA Substance Registry System	Piperazine, 1-(phenylmethyl)- (2759-28-6)

Safety Information

Hazard Codes	C,Xi
Risk Statements	34
Safety Statements	26-36/37/39-45
RIDADR	UN 3267 8/PG 2
WGK Germany	3
F	9
Hazard Note	Irritant
HazardClass	8
PackingGroup	III
HS Code	29335995

MSDS Information

Provider	Language
1-Benzylpiperazine	English
SigmaAldrich	English

1-Benzylpiperazine Usage And Synthesis

Chemical Properties	clear colorless to yellow liquid
Definition	ChEBI: A tertiary amino compound that is piperazine substituted by a benzyl group at position 1. It is a serotonergic agonist used as a recreational drug.

1-Benzylpiperazine Preparation Products And Raw materials

Raw materials	Piperazine
Preparation Products	1-Boc-(4-benzyl)piperazine-->2-(4-BENZYLPIPERAZINO)BENZALDEHYDE-->2-[4-(TERT-BUTYL)PHENOXY]-5-NITROBENZALDEHYDE-->1-(2-AMINOETHYL)-4-BENZYLPIPERAZINE-->1-(1-Methyl-4-piperidinyl)piperazine-->Meclozine-->3-(4-BENZYL-PIPERAZIN-1-YL)-PROPIONIC ACID-->BUCLIZINE-->N-METHYL-2-PIPERAZIN-1-YLACETAMIDE

Pifarnine Piperacillin (4-(BENZO[3,4-D]1,3-DIOXOLAN-5-YLMETHYL)PIPERAZINYL)(METHYLAMINO)METHANE-1-THIONE 3-(4-BENZO[1,3]DIOXOL-5-YLMETHYL-PIPERAZIN-1-YL)-PROPIONIC ACID HYDRAZIDE (4-(BENZO[D]1,3-DIOXOLEN-5-YLMETHYL)PIPERAZINYL)-N-((4-METHYLPHENYL)SULFONYL)FORMAMIDE PERALOPRIDE Benzyl chloride AKOS BBS-00000758 1-(2-[4-Chlorophenoxy]acetyl)-4-(3,4-methylenedioxybenzyl)piperazine 4-(BENZO[3,4-D]1,3-DIOXOLAN-5-YLMETHYL)-1-((2,4,6-TRIMETHYLPHENYL)SULFONYL)PIPERAZINE Phenylacetone 4-(BENZO[D]1,3-DIOXOLEN-5-YL(4-METHYLPIPERAZINYL)METHYL)-3-METHYL-1-PHENYL-2-PYRAZOLIN-5-ONE 1-(1,3-BENZODIOXOL-5-YLMETHYL)-4-(CHLOROACETYL)PIPERAZINE HYDROCHLORIDE FENOVERINE 5-[4-(1,3-BENZODIOXOL-5-YLMETHYL)PIPERAZINO]-1H-1,2,4-TRIAZOL-3-AMINE medibazine 1-Benzylpiperazine 1-(Phenylmethyl)piperazine

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