Ethyl Isocyanatoacetate

Ethyl Isocyanatoacetate Basic information
Product Name:Ethyl Isocyanatoacetate
Synonyms:ISOCYANATOACETIC ACID ETHYL ESTER;ETHYL ISOCYANATOACETATE;ETHYL 2-ISOCYANATOACETATE;CARBETHOXYMETHYL ISOCYANATE;Ethoxycarbonylmethyl isocyanate;ethoxycarbonylmethylisocyanate;Ethyl 2-isocyanotoacetate;ethylglycolateisocyanate
CAS:2949-22-6
MF:C5H7NO3
MW:129.11
EINECS:220-967-4
Product Categories:Isocyanates;Nitrogen Compounds;Organic Building Blocks
Mol File:2949-22-6.mol
Ethyl Isocyanatoacetate Structure
Ethyl Isocyanatoacetate Chemical Properties
Boiling point 67-68 °C/11 mmHg (lit.)
density 1.151 g/mL at 25 °C (lit.)
refractive index n20/D 1.422(lit.)
Fp 163 °F
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
form Liquid
color Clear colorless
Specific Gravity1.151
Water Solubility Reacts with water.
Sensitive Moisture Sensitive
BRN 970503
CAS DataBase Reference2949-22-6(CAS DataBase Reference)
EPA Substance Registry SystemAcetic acid, isocyanato-, ethyl ester (2949-22-6)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 36/37/38-42
Safety Statements 23-26-36
RIDADR 2206
WGK Germany 3
RTECS AI4450000
21
TSCA Yes
HazardClass 6.1
PackingGroup III
HS Code 29291000
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
Ethyl Isocyanatoacetate Usage And Synthesis
Chemical PropertiesClear colorless liquid
UsesEthyl isocyanate is a carboxylate organic compound and can be used in various chemial synthesis.
Ethyl isocyanatoacetate has been used in the preparation of:
6-(carboxymethylureido)-(±)-nicotine (CMUNic), nicotine immunogen
ethyl 8-carbamoyl-4-oxo-3,4-dihydroimidazo[5,1-d]-1,2,3,5-tetrazin-3-ylacetate
imidazo[1,2-c]-quinazoline-2,5-(3H,6H)dione
HazardModerately toxic by ingestion and inhalation.
Ethyl Isocyanatoacetate Preparation Products And Raw materials
Preparation ProductsEthyl 2-({N''-[(tert-Butoxy)carbonyl]hydrazinecarbonyl}amino)acetate-->Ethyl oxazole-4-carboxylate-->ETHYL UREIDOACETATE-->N-BETA(AMINOETHYL)-GAMMA-AMINOPROPYLMETHYLLDIMETHOXYSILANE
ETHYL 2-OXAZOLECARBOXYLATE ETHYL 2,3,4-TRI-O-BENZYL-1-THIO-BETA-L-FUCOPYRANOSIDE ETHYL 2-(BROMOMETHYL)ACRYLATE ETHYL 2-ISOCYANATO-3-PHENYLPROPIONATE ETHYL 2-ISOCYANATO-4-METHYLVALERATE 2-ISOCYANATO-3-PHENYLPROPIONIC ACID TERT-BUTYL ESTER 2-ISOCYANATOPROPIONIC ACID BENZYL ESTER ETHYL 2-ISOCYANATOPROPIONATE 2,6-DIISOCYANATOHEXANOIC ACID 2-ISOCYANATOETHYL ESTER (S)-(-)-2-ISOCYANATOGLUTARIC ACID DIETHYL ESTER ETHYL 2-CHLORO-3,3,3-TRIFLUORO-2-ISOCYANATOPROPANOATE L-Lysine Diisocyanate ETHYL 2-ISOCYANATO-4-(METHYLTHIO)BUTYRATE ETHYL 2-ISOCYANATO-3-METHYLBUTYRATE N-BUTYL ISOCYANATOACETATE Ethyl Isocyanatoacetate 2-ISOCYANATO-4-METHYLPENTANOIC ACID BENZYL ESTER 2-ISOCYANATO-PROPIONIC ACID TERT-BUTYL ESTER

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