2-Nitrophenylacetic acid

2-Nitrophenylacetic acid Basic information
Uses
Product Name:2-Nitrophenylacetic acid
Synonyms:Benzeneaceticacid,2-nitro-;2-(2-NITROPHENYL)ACETIC ACID;2-NITROPHENYLACETIC ACID;O-NITROPHENYLACETIC ACID;RARECHEM AL BO 0228;(2-Nitrophenly)AceticAcid;2-Nitrophenylaceticacid,99%;NITROPHENYLACETICACID
CAS:3740-52-1
MF:C8H7NO4
MW:181.15
EINECS:223-128-0
Product Categories:Intermediates;C8;Carbonyl Compounds;Carboxylic Acids;Indoles;Aromatic Phenylacetic Acids and Derivatives;Organic acids
Mol File:3740-52-1.mol
2-Nitrophenylacetic acid Structure
2-Nitrophenylacetic acid Chemical Properties
Melting point 137-140 °C (lit.)
Boiling point 314.24°C (rough estimate)
density 1.4283 (rough estimate)
refractive index 1.5468 (estimate)
storage temp. Sealed in dry,Room Temperature
form Crystalline Powder
pka4(at 25℃)
color Yellow to beige
BRN 1959243
CAS DataBase Reference3740-52-1(CAS DataBase Reference)
NIST Chemistry ReferenceBenzeneacetic acid, 2-nitro-(3740-52-1)
EPA Substance Registry System2-Nitrophenylacetic acid (3740-52-1)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-68
Safety Statements 26-36-37/39
WGK Germany 3
RTECS AJ1130000
TSCA Yes
HazardClass IRRITANT
HS Code 29163900
Toxicitymmo-sat 500 mg/plate MUREAV 170,11,86
MSDS Information
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2-(2-Nitrophenyl)acetic acid English
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2-Nitrophenylacetic acid Usage And Synthesis
Uses2-Nitrophenylacetic Acid is a useful research chemical.
Chemical Propertiesyellow to beige crystalline powder
Uses2-Nitrophenylacetic acid was used as an internal standard in the determination of the theophylline solubilizer salicylamide-O-acetic acid.
DefinitionChEBI: (2-nitrophenyl)acetic acid is a member of the class of phenylacetic acids that is phenylacetic acid in which the phenyl grup is substituted at the ortho- position by a nitro group. It is a C-nitro compound and a member of phenylacetic acids. It is functionally related to a nitrobenzene and a phenylacetic acid.
Safety ProfileMutation data reported. Forms an explosive mixture with thionyl chloride. When heated to decomposition it emits toxic fumes of NOx.
Purification MethodsThe acid crystallises as yellow needles from EtOH, EtOH/water and dry it over P2O5 under vacuum. The amide has m 160-161o (from *C6H6 plates or EtOH, needles). [Beilstein 9 III 2282, 9 IV 1687.]
2-Nitrophenylacetic acid Preparation Products And Raw materials
Preparation Products2-AMINOPHENYLACETIC ACID-->2-Aminophenethanol
6-BROMO-2-NITROPHENYLACETIC ACID (2-METHYL-6-NITRO-PHENYL)-ACETIC ACID Testosterone phenylacetate AKOS AU36-M255 2-NITROPHENYL ACETIC ACID ETHYL ESTER 2-NITRO-4-(TRIFLUOROMETHYL)PHENYLACETIC ACID Ethyl 2-(Chlorosulfonyl)acetate 4-Nitrophenylacetic acid trimethylsilyl ester 5-CARBOXY-2-NITROPHENYLACETIC ACID ρ-Nitrobenzenesulphonic acid 5-(METHOXYCARBONYL)-2-NITROPHENYLACETIC ACID METHYL ESTER BIS(2,4-DINITROPHENYL)ACETIC ACID ETHYL ESTER METHYL 2,4-DINITROPHENYLACETATE 4,5-DICHLORO-2-NITROPHENYLACETIC ACID phosphoric acid 2-Carboxy-6-nitrobenzeneacetic acid Nitrophenyl 2-METHYL-3-NITROPHENYLACETIC ACID

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