ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards 4,4'-(4H-1,2,4-TRIAZOL-4-YLMETHYLENE)BIS BENZONITRILE

4,4'-(4H-1,2,4-TRIAZOL-4-YLMETHYLENE)BIS BENZONITRILE

4,4'-(4H-1,2,4-TRIAZOL-4-YLMETHYLENE)BIS BENZONITRILE Basic information
Product Name:4,4'-(4H-1,2,4-TRIAZOL-4-YLMETHYLENE)BIS BENZONITRILE
Synonyms:4,4'-(4H-1,2,4-TRIAZOL-4-YLMETHYLENE)BIS BENZONITRILE;Iso Letrozole;Letrozole USP iMpurities;AMiodarone IMpurity-A;AMiodarone IMpurity-B;4,4'-(1H-1,3,4-triazol-1-ylMethylene)dibenzonitrile;Letrozole Related CoMpound A;4,4'-(4H-1,3,4-TRIAZOL-4-YLMETHYLENE)BIS
CAS:112809-52-6
MF:C17H11N5
MW:285.3
EINECS:
Product Categories:
Mol File:112809-52-6.mol
4,4'-(4H-1,2,4-TRIAZOL-4-YLMETHYLENE)BIS BENZONITRILE Structure
4,4'-(4H-1,2,4-TRIAZOL-4-YLMETHYLENE)BIS BENZONITRILE Chemical Properties
Melting point 239-243 °C
Boiling point 563.5±60.0 °C(Predicted)
density 1.21±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility Chloroform (Slightly, Heated), Methanol (Slightly)
pka2.48±0.10(Predicted)
form Solid
color Off-White to Pale Yellow
Safety Information
HS Code 2933998350
MSDS Information
4,4'-(4H-1,2,4-TRIAZOL-4-YLMETHYLENE)BIS BENZONITRILE Usage And Synthesis
UsesIsoletrozole is an impurity of Letrozole (L330100). Letrozole impurity A as per USP.
UsesIsoletrozole (Letrozole EP Impurity A) is an impurity of Letrozole (L330100). Letrozole impurity A as per USP.
4,4'-(4H-1,2,4-TRIAZOL-4-YLMETHYLENE)BIS BENZONITRILE Preparation Products And Raw materials
4-(1H-1,2,4-Triazol-1-ylmethyl)benzonitrile Neratinib Impurity Neratinib Impurity 6 4-[[3-Chloro-4-(2-pyridinylmethoxy)phenyl]amino]-7-ethoxy-6-[(1-methyl-2-pyrrolidinylidene)amino]-3-quinolinecarbonitrile LetrozoleN-Oxide 4,4',4''-Methylidenetrisbenzonitrile 4-((4-broMophenyl)(1H-1,2,4-triazol-1-yl)Methyl)benzonitrile 4,4'-(1H-1,2,4-TRIAZOL-1-YLMETHYLENE) BIS-BENZONITRILE 4-(4-CYANOBENZYL)-1,2,4-TRIAZOLE 4,4'-(1-METHYLENE) BIS-BENZONITRILE (S)-1-(4-CYANOPHENYL)ETHANAMINE 1,1-bis(4-methylphenyl)methanamine (R)-1-(4-CYANOPHENYL)ETHANAMINE 4,4'-(4H-1,2,4-TRIAZOL-4-YLMETHYLENE)BIS BENZONITRILE
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