| | 4-Iodophenol Basic information |
| | 4-Iodophenol Chemical Properties |
| Melting point | 92-94 °C(lit.) | | Boiling point | 138 °C5 mm Hg(lit.) | | density | 1.8573 | | Fp | 138°C/5mm | | storage temp. | Refrigerator | | solubility | Chloroform (Slightly), Methanol (Slightly) | | pka | 9.33(at 25℃) | | form | Crystals or Crystalline Powder | | color | Pink or beige to brown | | Water Solubility | slightly soluble | | Sensitive | Light Sensitive | | Merck | 14,5036 | | BRN | 1904544 | | Stability: | Stable. Incompatible with strong oxidizing agents. | | CAS DataBase Reference | 540-38-5(CAS DataBase Reference) | | NIST Chemistry Reference | Phenol, 4-iodo-(540-38-5) | | EPA Substance Registry System | p-Iodophenol (540-38-5) |
| | 4-Iodophenol Usage And Synthesis |
| Chemical Properties | light brown powder | | Uses | suzuki reaction | | Uses | 4-Iodophenol is used in chemiluminescence imaging assays and experiments, as diagnostic agents in order to detect cancer cells in patients. Also it is used in the synthesis of agonists towards the est
rogen β receptor. | | Uses | 4-Iodophenol is a chemical used in chemiluminescence imaging assays and experiments, as diagnostic agents in order to detect cancer cells in patients. Also it is used in the synthesis of agonists towards the estrogen β receptor. Also used in wide range of medicals industrial applications as well as in human and animal nutrition products such as pharmaceutical intermediates, and polarizing films for Liquid Crystal Display (LCD) chemicals. | | Definition | ChEBI: 4-iodophenol is an iodophenol. | | Synthesis Reference(s) | Organic Syntheses, Coll. Vol. 2, p. 355, 1943
The Journal of Organic Chemistry, 70, p. 8590, 2005 DOI: 10.1021/jo051191x
Tetrahedron Letters, 40, p. 6051, 1999 DOI: 10.1016/S0040-4039(99)01236-8 | | Purification Methods | Crystallise 4-iodophenol from pet ether (b 80-100o) or distil it in vacuo. If the material has a brown or violet color, then dissolve it in CHCl3, shake it with 5% sodium thiosulfate solution until is colourless. Dry (Na2SO4), extract, evaporate and disil the residue in vacuo. [Dains & Eberly Org Synth Coll Vol II 355 1948, Beilstein 6 IV 1074.] |
| | 4-Iodophenol Preparation Products And Raw materials |
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