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NCFJJNFEEPMRAQ-XMMPIXPASA-N

NCFJJNFEEPMRAQ-XMMPIXPASA-N Basic information
Product Name:NCFJJNFEEPMRAQ-XMMPIXPASA-N
Synonyms:NCFJJNFEEPMRAQ-XMMPIXPASA-N;Silodosin Dimer Impurity;Silodosin Impurity 4;1H-Indole-7-carboxamide, 5-[(2R)-2-[bis[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-2,3-dihydro-1-(3-hydroxypropyl)-;(R)-5-(2-(bis(2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl)amino)propyl)-1-(3-hydroxypropyl)indoline-7-carboxamide
CAS:1453221-45-8
MF:C35H41F6N3O6
MW:713.71
EINECS:
Product Categories:
Mol File:1453221-45-8.mol
NCFJJNFEEPMRAQ-XMMPIXPASA-N Structure
NCFJJNFEEPMRAQ-XMMPIXPASA-N Chemical Properties
Boiling point 716.2±60.0 °C(Predicted)
density 1.289±0.06 g/cm3(Predicted)
solubility DMSO (Slightly), Methanol (Slightly)
pka14.85±0.10(Predicted)
form Gel to Waxy Solid
color Colourless to Pale Yellow
Safety Information
MSDS Information
NCFJJNFEEPMRAQ-XMMPIXPASA-N Usage And Synthesis
UsesAn impurity in the synthesis of Silodosin (S465000), an α1a-adrenoceptor antagonist. It is used in treatment of benign prostatic hypertophy.
NCFJJNFEEPMRAQ-XMMPIXPASA-N Preparation Products And Raw materials
5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate Silodosin Impurity 26 Silodosin β-D-Glucuronide N-Carboxybenzyl O-Methyl Tri-acetate (R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-1-(3-hydroxypropyl)indoline-7-carboxamide(WXG00186) Silodosin Impurity 18 1-[3-(Benzoyloxy)propyl]-2,3-dihydro-5-(2-nitropropyl)-1H-indole-7-carbonitrile 1-(3-Hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]aMino]propyl]-1H-indole-7-carboxaMide 5-bromo-7-indolinecarbonitrile O-Acetyl Silodosin Silodosin Impurity 33 Silodosin-d6 5-(2-Aminopropyl)-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile S-Silodosin 1H-Indole-7-carbonitrile, 2,3-dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]aMino]propyl]- Silodosin Glucuronide Silodosin Carboxylic Acid Impurity Silodosin Impurity 2 HCl Silodosin β-D-Glucuronide Sodium Salt
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