2,2-Diphenylglycine

2,2-Diphenylglycine Basic information
Product Name:2,2-Diphenylglycine
Synonyms:LABOTEST-BB LT00159592;DIPHENYLGLYCIN;2,2-DIPHENYLGLYCINE;2,2-diphenyl-glycin;AMINODIPHENYLACETIC ACID;ALPHA,ALPHA-DIPHENYLGLYCINE;A,A-DIPHENYLGLYCINE;USP Phenytoin Related Compound A RS
CAS:3060-50-2
MF:C14H13NO2
MW:227.26
EINECS:221-299-6
Product Categories:Peptide Synthesis;Phenylglycine Derivatives;Unnatural Amino Acid Derivatives
Mol File:3060-50-2.mol
2,2-Diphenylglycine Structure
2,2-Diphenylglycine Chemical Properties
Melting point 245-247 °C (dec.) (lit.)
Boiling point 368.97°C (rough estimate)
density 1.231±0.06 g/cm3 (20 ºC 760 Torr)
refractive index 1.5780 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly, Heated), Methanol (Slightly, Heated)
pka1.38±0.10(Predicted)
form Powder
color White
Water Solubility It is sparingly soluble in water.
Stability:Hygroscopic
InChIKeyYBONNYNNFBAKLI-UHFFFAOYSA-N
CAS DataBase Reference3060-50-2(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
WGK Germany 3
RTECS MC0176000
HS Code 29224999
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
2,2-Diphenylglycine Usage And Synthesis
Description2, 2-Diphenylglycine is a highly similar analogue and the simplest aromatic peptide. It can be used as a synthesis reagent for amination reactions. It is a useful intermediate in pharmaceutical and in organic synthesis. Its derivatives have been also be shown to exhibit anticonvulsants activity and can be used for the treatment of pain.
Chemical Propertieswhite powder
Uses2,2-Diphenylglycine is used as a synthesis reagent for amination reactions. It acts as an intermediate in pharmaceutical and in organic synthesis.
ReferencesAnd, Meital Reches, and E. Gazit. "Formation of Closed-Cage Nanostructures by Self-Assembly of Aromatic Dipeptides." Nano Letters 4.4(2006):581-585.
https://www.alfa.com/en/catalog/B22650/
Harris, Robert H. "New uses for amino acid anticonvulsants for treatment of pain." EP, WO/2002/015922. 2002.

2,2-Diphenylglycine Preparation Products And Raw materials
Preparation ProductsN-(Benzhydrylidene)benzhydrylamine-->Benzophenone
D-Serine Phenytoin Impurity 4 Phenytoin Impurity 1 5,5-Diphenylhydantoin 5-(4-METHYLPHENYL)-5-PHENYLHYDANTOIN PHENYTOIN RELATED COMPOUND B (50 MG) (AL-PHA-((AMINOCARBONYL)AMINO)-ALPHA-PHENYL BEN-ZENEACETIC ACID) Phenytoin Impurity 2 Benzophenone 3a,6a-Diphenyloctahydroimidazo[4,5-d]imidazole-2,5-dione Benzil Phenytoin Impurity 3 n,2-diphenylglycin A,A-DIPHENYL-4-MORPHOLINEACETIC ACID, SODIUM SALT RARECHEM AQ A3 0001 AKOS 91996 2,2-Diphenylglycine ethyl 2-amino-2,2-diphenylacetate POTASSIUM 2-(3,5-DI-TERT-BUTYL-2-HYDROXYBENZYLIDENEAMINO)-2,2-DIPHENYLACETATE

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