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EMpagliflozin iMpurity 13

EMpagliflozin iMpurity 13 Basic information
Product Name:EMpagliflozin iMpurity 13
Synonyms:Empagliflozin Impurity 63;(2-chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6- (hydroxymethyl)tetrahydro-2H-pyran-2-yl)phenyl)(4-(((S)- tetrahydrofuran-3-yl)oxy)phenyl)methanone;Empagliflozin impurity 15/(2-chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6- (hydroxymethyl)tetrahydro-2H-pyran-2-yl)phenyl)(4-(((S)- tetrahydrofuran-3-yl)oxy)phenyl)methanone;Empagliflozin-12
CAS:2125472-55-9
MF:C23H25ClO8
MW:464.9
EINECS:
Product Categories:
Mol File:2125472-55-9.mol
EMpagliflozin iMpurity 13 Structure
EMpagliflozin iMpurity 13 Chemical Properties
Boiling point 710.3±60.0 °C(Predicted)
density 1.447±0.06 g/cm3(Predicted)
pka13.17±0.70(Predicted)
Safety Information
MSDS Information
EMpagliflozin iMpurity 13 Usage And Synthesis
Uses(2-Chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)phenyl)(4-(((S)-tetrahydrofuran-3-yl)oxy)phenyl)methanone is an impurity of Empagliflozin (E521510), a novel, potent and selective SGLT-2 inhibitor. It improves glycaemic control syndrome in diabetic rats.
EMpagliflozin iMpurity 13 Preparation Products And Raw materials
(2-Chloro-5-iodophenyl)(4-fluorophenyl)methanone Ethane, 2,2-dichloro-1,1,1-trimethoxy- (R)-3-(4-(5-broMo-2-chlorobenzyl)phenoxy)tetrahydrofuran (3R,4S,5S,6R)-2-[4-chloro-3-[[4-[(3S)-oxolan-3-yl]oxyphenyl]methyl]phenyl]-6-(hydroxymethyl)-2-methoxyoxane-3,4,5-triol EMpagliflozin iMpurity 10 Butanoic acid, 4-chloro-3-hydroxy-, (3S)- Methanone, (5-chloro-2-iodophenyl)(2-fluorophenyl)- Ethane, 1,1,1-trichloro-2,2,2-trimethoxy- (5-bromo-2-chlorophenyl)(4-fluorophenyl)methanone 1-chloro-4-(β-D-glucopyranos-1-yl)-2-[4-((S)-tetrahydrofuran-3-yloxy)benzyl]benzene Empagliflozin Impurity 32 (2-Chloro-5-iodophenyl)[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methanone (S)-(5-broMo-2-chlorophenyl)(4-(tetrahydrofuran-3-yloxy)phenyl)Methanone Empagliflozin Impurity Engleet net impurity 07 (R)-3-(4-(2-chloro-5-iodobenzyl)phenoxy)tetrahydrofuran (3R,4S,5S,6R)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxyMethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol Ethyl S-4-chloro-3-hydroxybutyrate
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