1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt)

1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt) Basic information
Product Name:1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt)
Synonyms:1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt);1,2-Dioctadecanoyl-sn-glycero-3-phospho-(1′-rac-glycerol) sodium salt;L-α-Phosphatidyl-DL-glycerol, distearoyl;Octadecanoic acid (1R)-1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester monosodium salt;1,2-Distearoyl-sn-glycero-3-PG (sodium salt);1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHO-(1'-RAC-GLYCEROL) (SODIUM SALT);18:0 PG;DSPG;PG(18:0/18:0);18:0 PG;1,2-Dioctadecanoyl-sn-glycero-3-phospho-(1′-rac-glycerol) sodium salt, 1,2-Distearoyl-sn-glycero-3-phosphoglycerol, L -α-Phosphatidyl-DL-glycerol, distearoyl, DSPG-Na, Octadecanoic acid (1R)-1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-eth
CAS:200880-42-8
MF:C81H159Na2O16P
MW:1466.072861
EINECS:
Product Categories:
Mol File:200880-42-8.mol
1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt) Structure
1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt) Chemical Properties
storage temp. -20°C
solubility Chloroform:Methanol:Water = 2:1:0.1 (Very Slightly)
form Solid
color White to Off-White
Stability:Hygroscopic
Safety Information
WGK Germany 3
MSDS Information
1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt) Usage And Synthesis
DescriptionDSPG, also known as 1,2-Distearoyl-sn-glycero-3-phosphoglycerol, is a phospholipid molecule with phosphate polar head connected to two non-polar lipid (stearic acid) by a glycerol molecule. In water, the molecule can orient itself into lipid bilayer and can be used for drug encapsulation, such as drug loaded liposomes or nanoparticles.
Uses1,2-Distearoyl-sn-glycero-3-phospho-rac-(1-glycerol) Sodium Salt is used to prepare polyethyleneglycol-modified liposomal doxorubicin for therapies against drug resistant tumors. It is also used in the PEGylated liposomal drug formulation of the anti-cancer agent oxaliplatin.
1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt) Preparation Products And Raw materials
1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE 1-MYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROYL L-BETA,GAMMA-DIPALMITOYL-ALPHA-PHOSPHATIDIC ACID DISODIUM SALT L-ALPHA-PHOSPHATIDYLCHOLINE, DISTEAROYL 1,2-DI[(CIS)-9-OCTADECENOYL]-SN-GLYCEROL-3-PHOSPHO-[1-RAC-GLYCEROL] SODIUM SALT 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATIDYL-RAC-GLYCEROL, NA SALT 1,2-DI 3,7,11,15-TETRAMETHYLHEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DiMyristoyl-sn-glycero-3-phospho-rac-(1-glycerol) SodiuM Salt 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHO-L-SERINE (MONOSODIUM SALT) 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodiuM salt) 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine 1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHO-L-SERINE SODIUM SALT

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