Betamethasone 17-Propionate 21-Mesylate

Betamethasone 17-Propionate 21-Mesylate Basic information
Product Name:Betamethasone 17-Propionate 21-Mesylate
Synonyms:(11β,16β)-9-Fluoro-11-hydroxy-16-Methyl-21-[(Methylsulfonyl)oxy]-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione;9-Fluoro-11β,17,21-trihydroxy-16β-Methylpregna-1,4-diene-3,20-dione 21-Methanesulfonate 17-Propionate;BetaMethasone 17-Propionate 21-Mesylate;Clobetasol Propionate EP Impurity I;Clobetasol Propionate Impurity 9(Clobetasol Propionate EP Impurity I);[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-17-(2-methylsulfonyloxyacetyl)-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate;Clobetasol Propionate EP IMP I;Pregna-1,4-diene-3,20-dione, 9-fluoro-11-hydroxy-16-methyl-21-[(methylsulfonyl)oxy]-17-(1-oxopropoxy)-, (11β,16β)-
CAS:15423-80-0
MF:C26H35FO8S
MW:526.61
EINECS:
Product Categories:Impurities;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
Mol File:15423-80-0.mol
Betamethasone 17-Propionate 21-Mesylate Structure
Betamethasone 17-Propionate 21-Mesylate Chemical Properties
Melting point 177-179 °C(Solv: water (7732-18-5); ethanol (64-17-5))
Boiling point 659.2±55.0 °C(Predicted)
density 1.33±0.1 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Very Slightly)
pka12.87±0.70(Predicted)
form Solid
color Pale Yellow to Yellow
Stability:Hygroscopic
Safety Information
MSDS Information
Betamethasone 17-Propionate 21-Mesylate Usage And Synthesis
UsesBetamethasone 17-Propionate 21-Mesylate is the 21-mesylate analogue of Betamethasone 17-Acetate (B327015) with antiinflammatory activity.
Betamethasone 17-Propionate 21-Mesylate Preparation Products And Raw materials
21-Chloro-9-fluoro-11β,17-dihydroxy-16β-Methylpregn-4-ene-3,20-dione 17-Propionate Betamethasone 17-valerate Betamethasone Impurity 16 TUIYCBORCUOUBA-DEGNENOVSA-N 9-Fluoro-11b,17,21-trihydroxy-16a-methylpregna-1,4-diene-3,20-dione 17-valerate (8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid Betamethasone 17,21-dipropionate Betamethasone Tripropionate Betamethasone EP Impurity J Betamethasone EP Impurity F Betamethasone Impurity 38 Betamethasone EP Impurity I 11-Keto Betamethasone BetaMethasone 9,11-Epoxide 17,21-Dipropionate Betamethasone Impurity 31 11alpha,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione Clobetasol 9-fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 21-(hydrogen phosphonate)

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