ChemicalBook Product Catalog Biochemical Engineering Inhibitors Neuronal Signaling GluR antagonist VU 0364770

VU 0364770

VU 0364770 Basic information
Product Name:VU 0364770
Synonyms:VU 0364770;2-PyridinecarboxaMide, N-(3-chlorophenyl)-;N-(3-Chlorophenyl)picolinamide;N-(3-chlorophenyl)pyridine-2-carboxamide;VU 0364770 100MG;VU0364770;VU-0364770;VU 0364770 USP/EP/BP;SKL856
CAS:61350-00-3
MF:C12H9ClN2O
MW:232.67
EINECS:
Product Categories:Aromatics, Heterocycles;Inhibitors
Mol File:61350-00-3.mol
VU 0364770 Structure
VU 0364770 Chemical Properties
Melting point 81-83 °C
Boiling point 293.6±20.0 °C(Predicted)
density 1.341±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml; DMSO: 25 mg/ml; Ethanol: 5 mg/ml
form Powder
pka11.24±0.70(Predicted)
Safety Information
MSDS Information
VU 0364770 Usage And Synthesis
UsesN-(3-Chlorophenyl)-2-pyridinecarboxamide shows positive allosteric modulation at the mGlu4 receptors in combination with other antagonists resulting in treatment for the neurodegenerative Parkinson’s disease.
UsesN-(3-Chlorophenyl)-2-pyridinecarboxamide shows positive allosteric modulation at the mGlu4 receptors in combination with other antagonists resulting in treatment for the neurodegenerative Parkinson’s disease (1).
VU 0364770 Preparation Products And Raw materials
Preparation Products2-AMINO-4-CHLOROBENZOTRIFLUORIDE
VU-29 VU0661013 VU0650786 VU 0364439 VU 0360223 VU 0357121 VU 0365114 VU 0360172 3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine 5-Amino-3,4-dimethyl-thieno[2,3-c]pyridazine-6-carboxylic acid 4-trifluoromethanesulfonyl-benzylamide (1R,2R)-N-([S]-1-{4-[5-broMo-2-oxo-2,3-dihydro-1H-benzo(d)iMidazol-1-yl]piperidin-1-yl}propan-2-yl)-2-phenylcyclopropanecarboxaMide VU 6008667 1-(4-Methoxybenzyl)-5-trifluoromethoxyisatin N-(4-Chloro-3-methoxyphenyl)-2-pyridinecarboxamide VU0483605 VU0810464 VU 591 hydrochloride VU6005649
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