ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards Desfluoro EzetiMibe

Desfluoro EzetiMibe

Desfluoro EzetiMibe Basic information
Product Name:Desfluoro EzetiMibe
Synonyms:Desfluoro EzetiMibe;(3R,4S)-3-[(3S)-3-(4-Fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-1-phenyl-2-azetidinone;1-Desfluoro EzetiMibe;EzetiMibe Desfluoro Analog;(3R,4S)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one;(3R,4S)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one;Ezetimibe-5;Ezetimibe impuriry 7/Desfluoro Ezetimibe/(3R,4S)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one
CAS:302781-98-2
MF:C24H22FNO3
MW:391.4347832
EINECS:
Product Categories:Impuities;Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:302781-98-2.mol
Desfluoro EzetiMibe Structure
Desfluoro EzetiMibe Chemical Properties
Melting point >78°C (dec.)
Boiling point 642.8±55.0 °C(Predicted)
density 1.293±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
pka9.72±0.30(Predicted)
form Solid
color White to Pale Yellow
Stability:Hygroscopic
Safety Information
MSDS Information
Desfluoro EzetiMibe Usage And Synthesis
UsesAn impurity of the cholesterol absorption inhibitor Ezetimibe (E975000). Ezetimibe Desfluoroaniline Analog (USP).
Desfluoro EzetiMibe Preparation Products And Raw materials
ent-EzetiMibe EzetiMibe (3R,4R,3'S)-IsoMer (R)-3-((S)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one (3R,4R)-1-(4-fluorophenyl)-3-((R)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one (3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one 4-Benzyloxybenzaldehyde Ezetimibe Impurity (3R,4S)-1-(3-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one (S)-3-((2R,5R)-5-(4-fluorophenyl)-2-((S)-(4-fluorophenylaMino)(4-hydroxyphenyl)Methyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one (3S,4R)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one EZM-K (S)-3-((R)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one Ezetimibe 4-Fluoroaniline (3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One (3S,4S)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one EzetiMibe IMpurity 1 (3S,4S)-1-(4-fluorophenyl)-3-((R)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one
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