6,11-Di-O-Methyl ErythroMycin

6,11-Di-O-Methyl ErythroMycin Basic information
Product Name:6,11-Di-O-Methyl ErythroMycin
Synonyms:6,11-Di-O-Methyl ErythroMycin;11-O-MethylclarithroMycin;Clarithromycin EP Impurity E/3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-13-hydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-7,12-di;Clarithromycin EP Impurity E (USP RC A);Clarithromycin Impurity 5(Clarithromycin EP Impurity E);Clarithromycin EP Impurity E;Erythromycin, 6,11-di-O-methyl-;Clarithromycin EP Impurity E/ Clarithromycin Related Compound A (6,11-Di-O-methylerythromycin A)
CAS:81103-14-2
MF:C39H71NO13
MW:761.98
EINECS:
Product Categories:Carbohydrates & Derivatives;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:81103-14-2.mol
6,11-Di-O-Methyl ErythroMycin Structure
6,11-Di-O-Methyl ErythroMycin Chemical Properties
Melting point 252-257 °C(Solv: dichloromethane (75-09-2); ethyl ether (60-29-7))
Boiling point 808.6±65.0 °C(Predicted)
density 1.16±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly, Heated)
form neat
pka12.96±0.70(Predicted)
color White to Off-White
Safety Information
HS Code 2932206000
MSDS Information
6,11-Di-O-Methyl ErythroMycin Usage And Synthesis
UsesA Di-O-alkyl Erythromycin (E649950) analog with antibacterial activity.
Uses6,11-Di-O-methyl Erythromycin (Clarithromycin EP Impurity E) is a Di-O-alkyl Erythromycin (E649950) is an impurity of Clarithromycin (C559750). Clarithromycin impurity E per British Pharmacopoeia.
UsesA Di-O-alkyl Erythromycin (E649950) is an impurity of Clarithromycin (C559750). Clarithromycin impurity E per British Pharmacopoeia.
6,11-Di-O-Methyl ErythroMycin Preparation Products And Raw materials
3-O-Decladinosyl-6-O-Methylerythronolide A ERYTHROMYCIN OXIME 3-O-De(2,6-dideoxy-3-C-Methyl-3-O-Methyl-α-L-ribo-hexopyranosyl)-8,9,10,11-tetradehydro-9-deoxo-11,12-dideoxy-9,12-epoxy-6-O-MethylerythroMycin N-DEMETHYL ERYTHROMYCIN A N-Desmethyl Clarithromycin Clarithromycin Clarithromycin Impurity Q (10 mg) (N-oxide clarithromycin) ClarithroMycin IMpurity G (10E)-10,11-Didehydro-11-deoxy-6-O-MethylerythroMycin Clarithromycin (9Z)-O-Methyloxime CLARITHROMYCIN OXIME Clarthromycin EP Impurity B Clarithromycin Impurity H Clarithromycin (9Z)-Oxime N-Desmethyl Clarithromycin (9E)-Oxime ClarithroMycin EP IMpurity F 4'',6-Di-O-MethylerythroMycin 16-hydroxyclarithromycin

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