ent-LaMivudine

ent-LaMivudine Basic information
Product Name:ent-LaMivudine
Synonyms:(2S-cis)-4-AMino-1-[2-(hydroxyMethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyriMidinone;2',3'-Dideoxy-3'-thiacytidine;4-AMino-1-[(2S,5R)-2-(hydroxyMethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyriMidinone;cis(+)-2-HydroxyMethyl-5-(cytosin-1-yl)-1,3-oxathiolane;NSC 620753;4-amino-1-((2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one;Lamivudine Impurity 4(Lamivudine EP Impurity D);ent-LaMivudine
CAS:134680-32-3
MF:C8H11N3O3S
MW:229.26
EINECS:
Product Categories:Amines;Anti-virals;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Amines, Anti-virals, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds;Sulfur & Selenium Compounds
Mol File:134680-32-3.mol
ent-LaMivudine Structure
ent-LaMivudine Chemical Properties
Melting point 171.4 °C(Solv: water (7732-18-5); methanol (67-56-1))
Boiling point 475.4±55.0 °C(Predicted)
density 1.73±0.1 g/cm3(Predicted)
storage temp. Hygroscopic, Refrigerator, Under Inert Atmosphere
solubility DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form Solid
pka13.83±0.10(Predicted)
color White to Off-White
Stability:Hygroscopic
Safety Information
MSDS Information
ent-LaMivudine Usage And Synthesis
Usesent-Lamivudine (Lamivudine EP Impurity D) is an enantiomer of Lamivudine (L172500); an antiviral that inhibits HIV-reverse transcriptase.
ent-LaMivudine Preparation Products And Raw materials
(2R-cis)-5-(4-aMino-2-oxo-1(2H)-pyriMidinyl)-1,3-oxathiolane-2-carboxylic Acid Lamivudine EP Impurity A Aids004768 Lamivudine Salicylic acid lamivudine sulfoxide Lamivudine Impurity 1 Cytosine 5'-Epi-LaMivudine TROXACITABINE 4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one Lamivudine EP Impurity B Uracil

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