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| | SINENSETIN Basic information |
| Product Name: | SINENSETIN | | Synonyms: | Orange flavonoids;6-Hydroxyluteolin 5,6,7,3′,4′-pentamethyl ether;SINENSETIN;3',4',5,6,7-PENTAMETHOXYFLAVONE;5,6,7,3',4'-PENTAMETHOXYFLAVONE;5,6,7,3'',4''-PENTAMETHOXYFLAVONE WITH HPLC;2-(3,4-Dimethoxyphenyl)-5,6,7-trimethoxy-4H-1-benzopyran-4-one;Pedalitin permethyl ether | | CAS: | 2306-27-6 | | MF: | C20H20O7 | | MW: | 372.37 | | EINECS: | | | Product Categories: | Penta-substituted Flavones;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 2306-27-6.mol |  |
| | SINENSETIN Chemical Properties |
| Melting point | 174-176°C | | Boiling point | 547.8±50.0 °C(Predicted) | | density | 1.244±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: soluble3mg/mL, clear (warmed) | | form | powder | | color | white to beige | | BRN | 345748 | | LogP | 2.634 (est) | | CAS DataBase Reference | 2306-27-6(CAS DataBase Reference) |
| Hazard Codes | T | | Risk Statements | 25 | | Safety Statements | 22-24/25-45 | | WGK Germany | 3 | | HS Code | 29329990 |
| | SINENSETIN Usage And Synthesis |
| Uses | Sinensetin, eupatorin, 3'-hydroxy-5,6,7,4'-tetramethoxyflavone and rosmarinic acid contents and antioxidative effect of Orthosiphon stamineus from Malaysia. | | Uses | antiangiogenesis, antidiabetic | | Uses | Sinensetin exhibits anti-fungal, anti-histamine activity; induce cell differentiation, inhibition of linoleic acid oxidation, inhibition of white blood cells in the human zona protein Interleukin -1-i
nduced expression of tissue factor. | | Definition | ChEBI: A pentamethoxyflavone that is flavone substituted by methoxy groups at positions 5, 6, 7, 3' and 4' respectively. | | General Description | This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG | | Biochem/physiol Actions | Sinensetin is a citris flavonoid with anti-inflammatory and anti-proliferative activity. It has also been shown to enhance adipogenesis and lipolysis. |
| | SINENSETIN Preparation Products And Raw materials |
| Raw materials | (E)-3-(3,4-dimethoxyphenyl)-1-(6-hydroxy-2,3,4-trimethoxyphenyl)prop-2-en-1-one-->2-Propen-1-one, 3-(3,4-dimethoxyphenyl)-1-(2,4,6-trimethoxyphenyl)--->4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-hydroxy-5,6-dimethoxy--->6-hydroxyluteolin-->3,6-DIHYDROXY-2,4-DIMETHOXYACETOPHENONE-->Desmethoxycentaureidin-->3-(3,4-DIMETHOXY-PHENYL)-PROPYNOIC ACID-->3,4-DIMETHOXYBENZOIC ACID ANHYDRIDE-->3,4,5-Trimethoxyphenol-->2',4',6'-TRIMETHOXYACETOPHENONE-->2,3,4-TRIMETHOXY-6-HYDROXYACETOPHENONE-->3,4-DIMETHOXYBENZOYL CHLORIDE-->Veratraldehyde-->3,4,5-Trimethoxy benzoic acid-->Dimethyl sulfate |
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