2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione

2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione Basic information
Product Name:2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione
Synonyms:2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione;N-(3-Chloro-2-hydroxypropyl)phthalimide;Rivaroxaban Impurity 120;1H-Isoindole-1,3(2H)-dione, 2-(3-chloro-2-hydroxypropyl)-;2-(3-Chloro-2-hydroxypropyl)isoindoline-1,3-dione
CAS:19667-37-9
MF:C11H10ClNO3
MW:239.65
EINECS:
Product Categories:
Mol File:19667-37-9.mol
2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione Structure
2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione Chemical Properties
Melting point 95-96.5 °C
Boiling point 405.4±35.0 °C(Predicted)
density 1.444±0.06 g/cm3(Predicted)
pka13.25±0.20(Predicted)
Safety Information
MSDS Information
2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione Usage And Synthesis
Uses2-(3-Chloro-2-hydroxypropyl)-1H-isoindole-1,3(2H)-dione has been used in yeast biosynthesis of (S)-adrenergic β-blockers by stereoselective reduction of haloketones. It has also been used in a validated LC-?MS?/MS method for the determination of three genotoxic impurities in rivaroxaban drug substance.
2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione Preparation Products And Raw materials

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