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| | 3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one Basic information |
| Product Name: | 3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one | | Synonyms: | 3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one;4',5,7-Trihydroxy-6-(3-methyl-2-butenyl)isoflavone;4',5,7-Trihydroxy-6-prenyl-isoflavone;5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one;Erythrinin B;Wighteone;5,7,4'-Trihydroxy-6-prenylisoflavone;5,7-dihydroxy-3-(4-hydroxyphenyl)-6-(3-methylbut-2-enyl)-1-benzopyran-4-one | | CAS: | 51225-30-0 | | MF: | C20H18O5 | | MW: | 338.35 | | EINECS: | | | Product Categories: | | | Mol File: | 51225-30-0.mol |  |
| | 3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one Chemical Properties |
| Melting point | 227 °C(Solv: methanol (67-56-1)) | | Boiling point | 586.1±50.0 °C(Predicted) | | density | 1.351±0.06 g/cm3(Predicted) | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | pka | 7.03±0.20(Predicted) | | form | powder | | color | Yellow | | Stability: | Light Sensitive |
| | 3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one Usage And Synthesis |
| Uses | Wighteone is a natural product derivative of Genistein (G350000). Genistein exhibits specific inhibitory activity against tyrosine kinases, including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors 2. uv(max)ethanol: 262.5 nm (e= 138). moderately sol. in hot alcohol. | | Definition | ChEBI: A member of the class of 7-hydroxyisoflavones that is isoflavone substituted by hydroxy groups at positions 5, 7 and 4' and a prenyl group at position 6. It has been isolated from Ficus mucuso. | | target | HSP (e.g. HSP90) | Antifection |
| | 3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one Preparation Products And Raw materials |
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