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| | METHYL 2,4-DIHYDROXY-3,6-DIMETHYLBENZOATE Basic information |
| Product Name: | METHYL 2,4-DIHYDROXY-3,6-DIMETHYLBENZOATE | | Synonyms: | MOUSSE DE METRA;VERAMOSS;VERAMOSS SPS;2,4-dihydroxy-3,6-dimethyl-benzoicacimethylester;Atraric acid;Benzoic acid, 2,4-dihydroxy-3,6-dimethyl-, methyl ester;Benzoicacid,2,4-dihydroxy-3,6-dimethyl-,methylester;Methyl 3,6-dimethyl-beta-resorcylate | | CAS: | 4707-47-5 | | MF: | C10H12O4 | | MW: | 196.2 | | EINECS: | 225-193-0 | | Product Categories: | Alphabetical Listings;Flavors and Fragrances;M-N | | Mol File: | 4707-47-5.mol |  |
| | METHYL 2,4-DIHYDROXY-3,6-DIMETHYLBENZOATE Chemical Properties |
| Melting point | 141-146 °C (lit.) | | Boiling point | 360.7±22.0 °C(Predicted) | | density | 1.251±0.06 g/cm3(Predicted) | | vapor pressure | 0.002Pa at 24℃ | | storage temp. | Store below +30°C. | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | pka | 8.63±0.28(Predicted) | | form | Powder | | Odor | at 10.00 % in dipropylene glycol. mossy oakmoss woody phenolic earthy | | Odor Type | mossy | | Water Solubility | 18mg/L at 24℃ | | LogP | 2.6 at 25℃ | | CAS DataBase Reference | 4707-47-5(CAS DataBase Reference) | | EPA Substance Registry System | Benzoic acid, 2,4-dihydroxy-3,6-dimethyl-, methyl ester (4707-47-5) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 2 | | TSCA | Yes | | HS Code | 2918 29 00 |
| | METHYL 2,4-DIHYDROXY-3,6-DIMETHYLBENZOATE Usage And Synthesis |
| Chemical Properties | Methyl 3,6-Dimethylresorcylate is an odor-determining constituent
of oakmoss absolute extract and forms colorless crystals (mp 145°C) with
a mossy–earthy odor. | | Uses | Methyl atratate is used in biological study as role of androgens in inducing distinct response of epithelial-mesenchymal transition factors in human prostate cancer cells. | | Preparation | Methyl 3,6-dimethylresorcylate is prepared by aromatization of corresponding
hydroxycyclohexenones, for example, by dehydrogenation with a suitable Nhaloimide.
The intermediate hydroxycyclohexenone can be obtained either by reaction of
dimethylmalonate with 4-hexen-3-one and 5-chloro-3-hexanone or by reaction
of methyl propionylacetate with alkyl crotonate.
Another route starts from the corresponding dimethyl-1,3-dihydroxybenzene,
which is carboxylated, and the resulting dihydroxymethylbenzoic acid is esterified.
| | Definition | ChEBI: Methyl beta-orcinolcarboxylate is a 4-hydroxybenzoate ester. | | Flammability and Explosibility | Notclassified | | Trade name | Atralone (Agan) |
| | METHYL 2,4-DIHYDROXY-3,6-DIMETHYLBENZOATE Preparation Products And Raw materials |
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