Difluoxacin hydrochloride

Difluoxacin hydrochloride Basic information
Brand Name(s) in US
Product Name:Difluoxacin hydrochloride
Synonyms:VETRANAL;6-FLUORO-1-(4-FLUOROPHENYL)-1,4-DIHYDRO-7-(4-METHYLPIPERAZINO)-4-OXO-3-QUINOLINECARBOXYLIC ACID HYDROCHLORIDE;DIFLUOXACIN HYDROCHLORIDE;DIFLOXACIN HCL;DIFLOXACIN HYDROCHLORIDE;Difluoxacin HCL;6-Fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid hydrochloride;3-Quinolinecarboxylic acid, 6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-, monohydrochloride
CAS:91296-86-5
MF:C21H20ClF2N3O3
MW:435.85
EINECS:1806241-263-5
Product Categories:DICURAL;Active Pharmaceutical Ingredients;Chiral Reagents;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:91296-86-5.mol
Difluoxacin hydrochloride Structure
Difluoxacin hydrochloride Chemical Properties
Melting point >245°C (dec.)
storage temp. Inert atmosphere,Room Temperature
solubility Soluble in aqueous buffer
form powder
CAS DataBase Reference91296-86-5(CAS DataBase Reference)
Safety Information
WGK Germany 3
RTECS VB2008975
MSDS Information
Difluoxacin hydrochloride Usage And Synthesis
Brand Name(s) in USDicural
DescriptionDifloxacin is a fluoroquinolone antibiotic. It is active against isolates of anaerobic bacteria, including B. fragilis, as well as Fusobacterium and Actinomyces species with MIC values ranging from ≤0.125 to 8 μg/ml. It eliminates E. coli and B. fragilis infection in a rat intra-abdominal abscess model when administered at a dose of 40 mg/kg three times per day.
Chemical PropertiesOff-White to Pale Yellow Solid
Usesantibacterial, DNA gyrase inhibitor
UsesA quinolone antibacterial compound. Structurally related to norfloxacin
UsesA fluoroquinolone antibacterial structurally related to norfloxacin.
Difluoxacin hydrochloride Preparation Products And Raw materials
Levofloxacin HCL Capsule Sarafloxacin hydrochloride Isoquinoline Ofloxacin hydrochloride N-Aminoethylpiperazine Quinclorac Topotecan hydrochloride Difloxacin Ethoxyquin 2-Ethylhexyl ferulate Sarafloxacin 1-AdaMantanethylaMine Levodropropizine Difluoxacin hydrochloride Rufloxacin hydrochloride 4-FLUORODIPHENYLAMINE fluoro jade NORFLOXACIN HYDROCHLORIDE

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