5-Amino-2,4,6-triiodisophthaloyl acid dichloride

5-Amino-2,4,6-triiodisophthaloyl acid dichloride Basic information
Product Name:5-Amino-2,4,6-triiodisophthaloyl acid dichloride
Synonyms:5-Amino-2,4,6-Triiodoiso Phthaloyl Chloride;5-Amino-2,4,6-triiodisophthaloyl dichloride;5-Amino-2,4,6-Triiodo-1,3-Benzenedicarboxylic Acid Dichloride;5-Amino-2,4,6-triiodoisophthaloydichloride;5-Amino-2,4,6-Triodoisophthalo;5-AMINO-2,4,6-TRIIODOISOPHTALOYL CHLORIDE;5-amino-2,4,6-triodoisophthalolyl chloride 5-Amino-2,4,6-triiodo-1,3-benzenedicar-boxylic acid dichloride;5-amino-2,4,6-triiodo-1,3-benzenedicarbonyldichloride
CAS:37441-29-5
MF:C8H2Cl2I3NO2
MW:595.73
EINECS:417-220-1
Product Categories:Intermediate of Ioversol
Mol File:37441-29-5.mol
5-Amino-2,4,6-triiodisophthaloyl acid dichloride Structure
5-Amino-2,4,6-triiodisophthaloyl acid dichloride Chemical Properties
Melting point 231°C(lit.)
Boiling point 566.9±50.0 °C(Predicted)
density 2.826±0.06 g/cm3(Predicted)
vapor pressure 0.018Pa at 20℃
storage temp. Refrigerator, under inert atmosphere
solubility Acetone (Slightly), Methanol (Very Slightly)
pka-3.45±0.10(Predicted)
form Solid
color Yellow toDark Brown
λmax233nm(MeOH)(lit.)
LogP3.7 at 20℃
CAS DataBase Reference37441-29-5(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,N
Risk Statements 43-51/53
Safety Statements 22-36/37-61
RIDADR 3077
HS Code 2922.49.3700
HazardClass 9
PackingGroup III
MSDS Information
5-Amino-2,4,6-triiodisophthaloyl acid dichloride Usage And Synthesis
Description5-Amino-2,4,6-triiodisophthaloyl acid dichloride is a triiodinated compound that has been shown to bind to the receptor for asialoglycoprotein. It is used in the diagnosis of liver and kidney diseases. 5-Amino-2,4,6-triiodisophthaloyl acid dichloride is taken up by tissues and organs and causes damage to these tissues. The chloride ion binds to the molecule, making it more water soluble. The lactobionic acid residue is then cleaved off by an enzyme in the cell called beta-galactosidase. This leaves a molecule containing iodine which can be detected with a diagnostic technique such as X-ray crystallography or nuclear magnetic resonance spectroscopy.
Chemical PropertiesYellow Solid
Uses5-Amino-2,4,6- triiodisophthaloyl acid dichloride is used in the preparation of trimeric X-ray contrast agents.
Flammability and ExplosibilityNotclassified
4-IODO-3-METHYLANILINE 2-IODOBENZOYL CHLORIDE 3,5-DIMETHYL-4-IODOANILINE 4-IODO-M-XYLENE 3,5,5-Trimethylhexanoyl chloride 2-IODO-5-METHYLANILINE 3-(Chloromethyl)benzoyl chloride 2,4-Diiodoaniline p-Iodobenzylchloride 2-Iodo-1,3-dimethylbenzene 2,4-DIIODO-3,5-DIMETHYLANILINE 3-Methylbenzoyl chloride 1,3-DIIODO-2,4-DIMETHYLBENZENE Isophthaloyl dichloride 4-Iodobenzoyl chloride 2,4,6-TRIIODO-PHENYLAMINE 2-Iodobenzyl chloride 1,3-Bis(chloromethyl)benzene

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