3,5-Difluoromandelic acid

3,5-Difluoromandelic acid Basic information
Product Name:3,5-Difluoromandelic acid
Synonyms:3,5-DIFLUOROMANDELIC ACID;3,5-DIFLUORO-ALPHA-HYDROXYPHENYLACETIC ACID;alpha-Hydroxy-3,5-difluorophenylacetic acid;3,5-DIFLUOROMANDELIC ACID 98+%;à-hydroxy-3,5-difluorophenylacetic acid;3,5-DIFLUORO-A-HYDROXYPHENYLACETIC ACID;2-(3,5-difluorophenyl)-2-hydroxyacetic acid;Benzeneacetic acid, 3,5-difluoro-a-hydroxy-
CAS:132741-31-2
MF:C8H6F2O3
MW:188.13
EINECS:670-875-7
Product Categories:Aryl Fluorinated Building Blocks;Building Blocks;C7-C8;Carbonyl Compounds;Carboxylic Acids;Chemical Synthesis;Fluorinated Building Blocks;Organic Building Blocks;Organic Fluorinated Building Blocks;Other Fluorinated Organic Building Blocks;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Miscellaneous;C10;Carbonyl Compounds;Carboxylic Acids
Mol File:132741-31-2.mol
3,5-Difluoromandelic acid Structure
3,5-Difluoromandelic acid Chemical Properties
Melting point 135-139 °C (lit.)
Boiling point 306.5±37.0 °C(Predicted)
density 1.522±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka3.10±0.10(Predicted)
form crystalline solid
color White
CAS DataBase Reference132741-31-2(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37/39
WGK Germany 3
HazardClass IRRITANT
HS Code 29181990
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
3,5-Difluoromandelic acid Usage And Synthesis
Chemical PropertiesWhite powder
General Description3,5-Difluoromandelic acid is also known as α-hydroxy-3,5-difluorophenylacetic acid. Racemic 3,5-difluoromandelic acid undergoes optical resolution in the presence of (1R,2R)-(-)-pseudoephedrine in isopropanol to afford (S)-form.
3,5-Difluoromandelic acid Preparation Products And Raw materials
Raw materials3,5-Difluorobenzaldehyde
1-(3,5-DIFLUOROPHENYL)ETHANOL Dichlorodifluoromethane 2-(3,5-difluorophenyl)acetaldehyde 1-(3-Fluorophenyl)ethanol Ethyl bromodifluoroacetate 4-Fluoromandelic acid 3-Fluorophenylacetic acid Ascoric Acid difluoroethane 3,5-Difluorophenylacetic acid PENTAFLUOROMANDELIC ACID 2,3,5,6-TETRAFLUOROMANDELIC ACID Polyvinylenedifluoride (S)-(+)-Mandelic acid 3-Fluorophenethyl alcohol 3,5-Difluoromandelic acid 2,4-DIFLUOROMANDELIC ACID 97%,2,4-DIFLUOROMANDELIC ACID Mandelic acid

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