ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Other amino acid derivatives L-Selenomethionine

L-Selenomethionine

L-Selenomethionine Basic information
Product Name:L-Selenomethionine
Synonyms:(S)-(+)-2-AMINO-4-(METHYLSELENO)BUTANOIC ACID;(S)-2-AMINO-4-(METHYLSELENO)BUTYRIC ACID;SEMET;SELENOMETHIONINE, L-(+)-;SELENO-L-METHIONINE;L-(+)-2-AMINO-4-(METHYLSELENO)BUTANOIC ACID;L-(+)-SELENOMETHIONINE;L-SELENOMETHIONINE
CAS:3211-76-5
MF:C5H11NO2Se
MW:196.11
EINECS:608-705-0
Product Categories:Seleno Amino Acid;Methionine [Met, M];Amino Acids;Antioxidant;Biochemistry;Biological-modified Amino Acids;Amino Acid Derivatives;Classes of Metal Compounds;Se (Selenium) Compounds;Semimetal Compounds;amino acid;3211-76-5
Mol File:3211-76-5.mol
L-Selenomethionine Structure
L-Selenomethionine Chemical Properties
Melting point 265 °C
alpha 18 º (c=1, 1N HCl)
Boiling point 320.8±37.0 °C(Predicted)
refractive index 18 ° (C=0.5, 2mol/L HCl)
storage temp. -20°C
solubility H2O: 50 mg/mL
pka2.26±0.10(Predicted)
form powder
color white to off-white
Water Solubility soluble
Merck 14,8441
InChIKeyRJFAYQIBOAGBLC-BYPYZUCNSA-N
LogP0.152 (est)
CAS DataBase Reference3211-76-5(CAS DataBase Reference)
Safety Information
Hazard Codes T,N
Risk Statements 23/25-33-50/53
Safety Statements 20/21-28-45-60-61-28A
RIDADR UN 3283 6.1/PG 2
WGK Germany 3
RTECS EK7713840
F 10
HazardClass 6.1
PackingGroup III
HS Code 29309090
MSDS Information
ProviderLanguage
L-(+)-Selenomethionine English
ACROS English
SigmaAldrich English
L-Selenomethionine Usage And Synthesis
Chemical PropertiesSolid
UsesA compound shown to increase expression of glutathione peroxidase
UsesSeleno-L-methionine has been used:
  • in toxicity studies in Japanese Medaka embryos
  • to study its effects on selenium status indicators in pregnant long-tailed macaques (Macaca Fascicularis)
  • to label proteins for single wavelength anomalous dispersion (SAD) phasing

DefinitionChEBI: The L-enantiomer of selenomethionine.
General DescriptionSeleno-L-Methionine (SeMet), an organic form of selenium is found in Cupriavidus metallidurans.
Biochem/physiol ActionsSeleno-L-Methionine (SeMet) is capable of repressing atopic dermatitis (AD)-like skin lesions. It can also prevent the expression of total immunoglobulin E (IgE) and interleukin 4 (IL-4). It can cause ecotoxicity as it is absorbed by fish through diet.
Selenomethionine[75Se] D-SELENOMETHIONINE Selenium (as Selenomethionine) L-SELENOMETHIONINE BLEND Fmoc-Selenomethionine FMOC-DL-SELENOMETHIONINE N-ACETYL-L-SELENOMETHIONIN SELENOMETHIONINE-ENRICHEDSALMON BOC-L-SELENOMETHIONINE DL-Selenomethionine SELENOMETHIONINE, L-(+)-(RG) BOC-DL-SELENOMETHIONINE SELENOMETHIONINE USP(CRM STANDARD) L-Selenomethionine DL-Selenomethionine-13C1 (methyl-13C1),DL-SELENOMETHIONINE-METHYL-13C1 L-Selenomethionine-13C1 (methyl-13C1) L-Selenomethionine Blend, 5,000 μg/g SELENOMETHIONINE, L-(+)-(REAGENT / STANDARD GRADE)
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