MEDICARPIN

MEDICARPIN Basic information
Product Name:MEDICARPIN
Synonyms:MEDICARPIN;3-HYDROXY-9-METHOXYPTEROCARPAN;[6aR,11aR,(-)]-6a,11a-Dihydro-9-methoxy-6H-benzofuro[3,2-c][1]benzopyran-3-ol;(L)-De-o-methylhomopterocarpan;6A,11A-Dihydro-9-methoxy-6H-benzofuro(3,2-C)(1)benzopyran-3-ol;6H-Benzofuro(3,2-C)(1)benzopyran-3-ol, 6A,11A-dihydro-9-methoxy-, cis- (8ci);L-3-Hydroxy-9-methoxypterocarpan;Nsc 350085
CAS:32383-76-9
MF:C16H14O4
MW:270.28
EINECS:
Product Categories:
Mol File:32383-76-9.mol
MEDICARPIN Structure
MEDICARPIN Chemical Properties
Melting point 127.5-128.5°
alpha D22 -226° (chloroform)
Boiling point 418.8±45.0 °C(Predicted)
density 1.319±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka9.50±0.20(Predicted)
form Powder
Safety Information
MSDS Information
MEDICARPIN Usage And Synthesis
UsesMedicarpin can be used to inhibit IL-8 release via interactions with toll-like receptor 4 and lipopolysaccharide. It can also be used to treat COVID-19.
DefinitionChEBI: (-)-medicarpin is the (-)-enantiomer of medicarpin. It has a role as a plant metabolite. It is an enantiomer of a (+)-medicarpin.
targetROS | JNK | Bcl-2/Bax | TNF-α | NF-kB | p65 | P450 (e.g. CYP17)
MEDICARPIN Preparation Products And Raw materials
Raw materials2''-Methoxyformononetin-->2''-HYDROXYFORMONONETIN-->(+)-Medicarpin-->2,4-Dimethoxyphenylacetic acid-->Resorcinol
2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one Naringenin 7-O-β-D-Glucuronide (Mixture of Diastereomers) hydroxygenkwanin Naringenin PONCIRIN MEDICAGOL 4',5-DIHYDROXY-7-METHOXYFLAVONE MOSLOFLAVONE GARDENIN B TRIFOLIRHIZIN (-)-PTEROCARPIN Phaseollin SANDWICENSIN NISSOLIN-9-O-METHYL ETHER HOMOPTEROCARPIN MEDICARPIN-3-O-GLUCOSIDE (-)-MAACKIAIN MEDICARPIN

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