4-Nitrophenylboronic acid pinacol ester

4-Nitrophenylboronic acid pinacol ester Basic information

Product Name:	4-Nitrophenylboronic acid pinacol ester
Synonyms:	4-NITROPHENYLBORONIC ACID PINACOL ESTER;4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)NITROBENZENE;4-Nitrobenzeneboronic acid, pinacol ester;4,4,5,5-tetramethyl-2-(4-nitrophenyl)-1,3,2-dioxaborolane;2-(4-Nitrophenyl)-4,4,5,5,-tetramethyl-1,3,2-dioxaborolane, 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)nitrobenzene;1,3,2-Dioxaborolane, 4,4,5,5-tetramethyl-2-(4-nitrophenyl)-;4-Nitrophenylboronic acid pinacol ester 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)nitrobenzene;-Nitrophenylboronic acid pinacol ester
CAS:	171364-83-3
MF:	C12H16BNO4
MW:	249.07
EINECS:
Product Categories:	Aryl Boronate Esters;Boronate Esters;Aryl;Boronic Acids and Derivatives;Chemical Synthesis;Organometallic Reagents;blocks;BoronicAcids;NitroCompounds;Boronic ester;Organoborons;Pyrimidines
Mol File:	171364-83-3.mol

4-Nitrophenylboronic acid pinacol ester Chemical Properties

Melting point	112-116 °C (lit.)
Boiling point	357.5±25.0 °C(Predicted)
density	1.14±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	powder or crystals
color	White to Orange to Green
Water Solubility	Slightly soluble in water.
CAS DataBase Reference	171364-83-3(CAS DataBase Reference)

Safety Information

MSDS Information

Provider	Language
SigmaAldrich	English

4-Nitrophenylboronic acid pinacol ester Usage And Synthesis

Chemical Properties	White solid
Uses	Reactant involved in: • ;Synthesis of aryl azides 1• ;Arylation of allylic chlorides2• ;Syntehsis of RNA conjugates3• ;Alkoxycarbonylation4• ;Synthesis of mTOR and PI3K inhibitors as antitumor agents5• ;Electrooxidative synthesis of biaryls6
Uses	suzuki reaction
Uses	4-Nitrobenzeneboronic acid pinacol ester is a reactant involved in synthesis of aryl azides, arylation of allylic chlorides, synthesis of RNA conjugates, alkoxycarbonylation, synthesis of mTOR and PI3K inhibitors as antitumor agents, electro oxidative synthesis of biaryls.
Synthesis Reference(s)	The Journal of Organic Chemistry, 60, p. 7508, 1995 DOI: 10.1021/jo00128a024

4-Nitrophenylboronic acid pinacol ester Preparation Products And Raw materials

Raw materials	Diazene, 1-(methylsulfonyl)-2-(4-nitrophenyl)--->4-Nitrophenylboronic acid-->1-Iodo-4-nitrobenzene-->Phenyl trifluoromethanesulfonate-->boranylbis(propan-2-yl)amine-->4-NITROPHENYL TRIFLUOROMETHANESULFONATE-->4-NITROBENZENEDIAZONIUM TETRAFLUOROBORATE-->4-Nitrobenzenesulfonyl chloride-->Pinacol-->4-Chloronitrobenzene-->Pinacolborane-->Bis(pinacolato)diboron
Preparation Products	4,4'-DINITROBIPHENYL-->Nitrobenzene

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