Pyrimidinetetramine sulfate

Pyrimidinetetramine sulfate Basic information
Product Name:Pyrimidinetetramine sulfate
Synonyms:pyrimidinetetrayltetraamine sulphate;PYRIMIDINE-2,4,5,6-TETRAMINE SULPHATE;2,4,5,6-TETRAAMINIOPYRIMIDINE SULFATE;2,4,5,6-TETRAAMINO-PYRIMIDINE SULFATE SALT;2,4,5,6-Tetraaminopyrimidine sulfate hydrate,98%;2,4,5,6-Tetraaminopyrimidine sulfate;6-TetraaMinopyriMidine sulfate;PyriMidine-2,4,5,6-tetraaMine sulfate
CAS:5392-28-9
MF:C4H10N6O4S
MW:238.22
EINECS:226-393-0
Product Categories:Building Blocks;C4 to C5;Aromatics;Chemical Synthesis;Heterocyclic Building Blocks;Heterocycle-Pyrimidine series;FINE Chemical & INTERMEDIATES;Amines;(intermediate of methotrexate);Pyrimidines;Building Blocks;Heterocyclic Building Blocks;Heterocycles;Intermediates;bc0001
Mol File:5392-28-9.mol
Pyrimidinetetramine sulfate Structure
Pyrimidinetetramine sulfate Chemical Properties
Melting point >300 °C(lit.)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly, Heated), Water (Very Slightly, Heated)
form Crystalline Powder
color Ochre to brown
Water Solubility slightly soluble
BRN 3785189
InChIKeyMQEFDQWUCTUJCP-UHFFFAOYSA-N
CAS DataBase Reference5392-28-9(CAS DataBase Reference)
EPA Substance Registry SystemPyrimidinetetramine, sulfate (1:1) (5392-28-9)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 22-24/25-37/39-26-36
WGK Germany 3
RTECS UV9738000
TSCA Yes
HS Code 29335990
MSDS Information
ProviderLanguage
2,4,5,6-Tetraaminopyrimidine sulfate English
ACROS English
SigmaAldrich English
ALFA English
Pyrimidinetetramine sulfate Usage And Synthesis
Chemical PropertiesLight yellow crystal powder
UsesIntermediate in the production of Methotrexate.
Purification MethodsPurify the salt by recrystallisation from H2O, 2N H2SO4 (20 parts, 67% recovery) or 0.1N H2SO4 (40 parts, 62% recovery), and dried in air. [UV: Konrad & Pfleiderer Chem Ber 103 722 1970, Malletta et al. J Am Chem Soc 69 1814 1947, Cavalieri et al. J Am Chem Soc 70 3875 1948, Beilstein 25 H 423, 25 III/IV 3106.]
2,4,5,6-TETRAAMINOPYRIMIDINE 2,4,5-Trifluorobenzonitrile sulfate Vanadyl sulfate Sodium sulfate 4,5,6-TRIAMINOPYRIMIDINE SULFATE D-Glucosamine sulfate 2,4,5,6-Tetraaminopyrimidine sulfate Potassium persulfate 4,6-DIAMINOPYRIMIDINE SULFATE Pyrimidinetetramine sulfate Colistin sulfate Aluminum sulfate SULFATE STANDARD Zinc sulfate heptahydrate Magnesium sulfate 4,5,6-Triaminopyrimidine sulfate hydrate Ammonium sulfate

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