4-Bromomethyl-1,2-dihydroquinoline-2-one

4-Bromomethyl-1,2-dihydroquinoline-2-one Basic information
Product Name:4-Bromomethyl-1,2-dihydroquinoline-2-one
Synonyms:4-Bromomethyl-2-quinolinol;4-Bromomethyl Carbostyril;2(1H)-QUINOLINONE, 4-(BROMOMETHYL)-;4-(BROMOMETHYL)-2(1H)-QUINOLINONE;4-BROMOMETHYLQUINOLINONE;4-BROMOMETHYL-1,2-DIHYDROQUINOLIN-2-ONE;4-BROMOMETHYL-1,2-DIHYDROQUINOLINE-2-ONE;3-[(2,2,2-trifluoro-1-oxoethyl)amino]benzoic acid
CAS:4876-10-2
MF:C10H8BrNO
MW:238.08
EINECS:679-473-6
Product Categories:Isoquinolines ,Others ,Quinolines ,Quinaldines;Quinolines, Quinazolines and derivatives;API intermediates;(intermediate of Rebamipide);4876-10-2
Mol File:4876-10-2.mol
4-Bromomethyl-1,2-dihydroquinoline-2-one Structure
4-Bromomethyl-1,2-dihydroquinoline-2-one Chemical Properties
Melting point 255-258°C
Boiling point 391.8±42.0 °C(Predicted)
density 1.542±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form powder to crystal
pka11.17±0.70(Predicted)
color White to Light yellow to Light orange
CAS DataBase Reference4876-10-2(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38-34
Safety Statements 26-36/37/39-45
Hazard Note Irritant
HazardClass 8
HS Code 29334900
MSDS Information
ProviderLanguage
ALFA English
4-Bromomethyl-1,2-dihydroquinoline-2-one Usage And Synthesis
Chemical PropertiesLight yellow to light reddish yellow solid
Uses4-Bromomethyl-2(1H)-quinolinone is a reagent used in the preparation of coumarins and 1-aza coumarins which has nti-microbial, anti-inflammatory, and analgesic activities.
4-Bromomethyl-1,2-dihydroquinoline-2-one Preparation Products And Raw materials
Raw materials4-Bromo-3-oxo-N-phenylbutanamide-->Aniline-->Acetoacetanilide
Preparation ProductsRebaMipide 3-Chloro IMpurity-->2-HYDROXY-4-METHYLQUINOLINE-->rebamipide
2-Hydroxy-4-methylpyridine 2-HYDROXY-4-METHYLQUINOLINE 4-bromomethyl-2(1H)-quinolinone (intermediate of rebamipide) 4'-Bromoacetophenone 4-Bromomethyl-2(1H)-Quinolinone,Rebamipide1087239 Mesotrione (1-BROMOMETHYL-VINYL)-BENZENE 2-Quinolinol Pyridine, 4-(bromomethyl)- (9CI) 2-Bromoacetophenone 4-Bromomethylbenzoic acid 1-BROMO-2-METHYL-BUT-2-ENE 4-BROMOMETHYL-7-METHYL-1H-QUINOLIN-2-ONE 4-Bromomethyl-1,2-dihydroquinoline-2-one 4-Methyl-2-pentanone 4-Bromomethyl Carbostryill 6-Hydroxy-2(1H)-3,4-dihydroquinolinone Methyl bromide

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