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| | (S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol Basic information |
| Product Name: | (S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol | | Synonyms: | 1,3-Dioxolane-4-methanol, 2,2-dimethyl-, (S)-;(S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol,98%;(4S)-(+)-2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxolane 98%;(S)-(+)-1,2-Isopropylideneglycerol, [(4S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-yl]methanol, (S)-Solketal;(S)-(+)-2,2-DiMethyl-1,3-Dioxalane-4-Methanol;(S)-(+)-2,2-DiMethyl-1,3-dioxolane-4-Methanol, 98% 5GR;D-1,2-O-ISOPROPYLIDENE-SN-GLYCEROL;D-(+)-1,2-ISOPROPYLIDENEGLYCEROL | | CAS: | 22323-82-6 | | MF: | C6H12O3 | | MW: | 132.16 | | EINECS: | 244-910-8 | | Product Categories: | Miscellaneous;Inhibitors;pharmacetical;Chiral Reagent;Chiral Reagents;Chiral Building Blocks;Dioxanes & Dioxolanes;Dioxolanes;Glycidyl Compounds, etc. (Chiral);Synthetic Organic Chemistry;Heterocycles | | Mol File: | 22323-82-6.mol |  |
| | (S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol Chemical Properties |
| alpha | 11 º (c=5, CH3OH) | | Boiling point | 82-83 °C14 mm Hg(lit.) | | density | 1.07 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.434 | | Fp | 176 °F | | storage temp. | 2-8°C | | solubility | Chloroform, Ethanol, Methanol | | form | Liquid | | pka | 14.20±0.10(Predicted) | | color | Clear colorless to light yellow | | Specific Gravity | 1.07 | | optical activity | [α]20/D +13.5°, neat | | Water Solubility | miscible | | Merck | 14,5213 | | BRN | 80118 | | Stability: | Stable. Flammable. Incompatible with oxidizing agents. | | InChIKey | RNVYQYLELCKWAN-YFKPBYRVSA-N | | CAS DataBase Reference | 22323-82-6(CAS DataBase Reference) | | NIST Chemistry Reference | L-Acetone glycerol(22323-82-6) |
| Safety Statements | 23-24/25 | | WGK Germany | 3 | | RTECS | JI0400000 | | F | 10 | | HS Code | 29329970 |
| | (S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol Usage And Synthesis |
| Chemical Properties | Colorless Oil | | Uses | (S)-(+)-2,3-O-Isopropylideneglycerol acts as a MEK inhibitor with antitumor activity. It is also employed in the preparation of a chiral allylic triol through extrusion of sulfur dioxide from an alfa,beta-epoxysulfone. | | General Description | (S)-(+)-1,2-Isopropylideneglycerol is a key building block for the synthesis of glycerides and of phosphoglycerides. |
| | (S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol Preparation Products And Raw materials |
| Raw materials | Sodium sulfate-->Acetone-->Ammonium chloride-->Sodium borohydride-->Zinc chloride-->Sodium periodate-->D-Mannitol-->D-Iditol, 1,2:5,6-bis-O-(1-methylethylidene)--->Silane, [[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methoxy](1,1-dimethylethyl)dimethyl- (9CI)-->1,3-Dioxolane-4-methanol, 2,2-dimethyl-, 4-acetate, (4R)--->1,3-Dioxolane-4-methanol, 2,2-dimethyl-, 4-benzoate, (4R)--->Benzene, 1,1'-(methoxyphenylmethylene)bis[4-methoxy--->(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol-->(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde-->(S)-4-BENZYLOXYMETHYL-2,2-DIMETHYL-1,3-DIOXOLANE-->L-Glyceraldehyde-->(R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXYLIC ACID METHYL ESTER-->1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol |
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