ChemicalBook Product Catalog Chemical Reagents Organic reagents Esters Phenyl ester compound PENTAFLUOROPHENYL TRIFLUOROACETATE

PENTAFLUOROPHENYL TRIFLUOROACETATE

PENTAFLUOROPHENYL TRIFLUOROACETATE Basic information
Product Name:PENTAFLUOROPHENYL TRIFLUOROACETATE
Synonyms:PFP-O-TFA;PENTAFLUOROPHENYL TRIFLUOROACETATE;PENTAFLUORPHENYL TRIFLUORACETATE;TRIFLUORO ACETIC ACID PENTAFLUORO PHENYL ESTER;TFA-OPFP;Pentafluoropfenyl Trifluoroacetate;Pentafluorophenyl trifluoroacetate,Trifluoroacetic acid pentafluorophenyl ester;Pentafluorophenyl trifluoroacetate, 98+%
CAS:14533-84-7
MF:C8F8O2
MW:280.07
EINECS:629-320-4
Product Categories:
Mol File:14533-84-7.mol
PENTAFLUOROPHENYL TRIFLUOROACETATE Structure
PENTAFLUOROPHENYL TRIFLUOROACETATE Chemical Properties
Melting point 4°C(lit.)
Boiling point 122-123 °C (lit.)
density 1.63 g/mL at 25 °C (lit.)
refractive index n20/D 1.368(lit.)
Fp 126 °F
storage temp. Keep in dark place,Sealed in dry,2-8°C
form Oil
Specific Gravity1.630
color Clear colorless
Water Solubility Soluble in water at 122.5°Cat760mmHg.
Sensitive Moisture Sensitive
BRN 2003848
CAS DataBase Reference14533-84-7(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,F
Risk Statements 10-36/37/38
Safety Statements 16-26-36
RIDADR UN 3272 3/PG 3
WGK Germany 3
HazardClass 3.2
PackingGroup III
HS Code 29159000
MSDS Information
ProviderLanguage
SigmaAldrich English
PENTAFLUOROPHENYL TRIFLUOROACETATE Usage And Synthesis
Chemical PropertiesClear colorless liquid
UsesPentafluorophenyl trifluoroacetate can be used:
  • In the esterification of 2′-carboxyrhodamine dye to form pentafluorophenyl ester as a single isomer.
  • As an acylating agent and a coupling agent for the peptide-type coupling of N-substituted glycine oligomers.
  • In the synthesis of pentafluorophenyl thiophene-3-acetate (PFPTA) by reacting with 3-thiopheneacetic acid.

UsesIt is used as a pharmaceutical intermediate.
PENTAFLUOROPHENYL TRIFLUOROACETATE Preparation Products And Raw materials
Preparation Products1,4-Benzenedicarboxylic acid, bis(pentafluorophenyl) ester-->FMOC-LYS(BOC)-OPFP
TRIFLUOROACETALDEHYDE HYDRATE Methyl trifluoroacetate O-(2,2,2-Trifluoroethyl)hydroxylamine hydrochloride PENTAFLUOROPHENYLHYDRAZINE Tetramethylammonium trifluoromethanethiolate Lithium hydroxide Phthalates TRIFLUOROMETHANESULFONIC ACID TRIFLUOROMETHYL ESTER PENTAFLUOROBENZYL BROMIDE Pentafluorophenol 2,3,5,6-Tetrafluorophenol 2,3,5,6-TETRAFLUOROANISOLE Trifluoroacetic acid PENTAFLUORO-(2,2,2-TRIFLUOROETHOXY)BENZENE 2,3,4,5,6-PENTAFLUOROANISOLE 2,3,5,6-TETRAFLUOROPHENYL TRIFLUOROACETATE PENTAFLUOROPHENYL TRIFLUOROACETATE PHENYL TRIFLUOROACETATE
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