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| | (-)-TEPHROSIN Basic information |
| Product Name: | (-)-TEPHROSIN | | Synonyms: | 13,13a-Dihydro-7a-hydroxy-9,10-dimethoxy-3,3-dimethyl-3H-bis[1]benzopyrano[3,4-b:6',5'-e]pyran-7(7aH)-one;Hydroxydeguelin;Isotephrosin;Deguelinol I;Tephrosin (synthetic);3H-Bis[1]benzopyrano[3,4-b:6',5'-e]pyran-7- (7aH)-one,13,13a-dihydro-7a-hydroxy-9,10- dimethoxy-3,3-dimethyl-,(7aR,13aR)-;Tephrosin >=95% (LC/MS-ELSD);(-)-TEPHROSIN USP/EP/BP | | CAS: | 76-80-2 | | MF: | C23H22O7 | | MW: | 410.42 | | EINECS: | | | Product Categories: | Miscellaneous Natural Products | | Mol File: | 76-80-2.mol |  |
| | (-)-TEPHROSIN Chemical Properties |
| Melting point | 198° (218-220°) | | Boiling point | 450.42°C (rough estimate) | | density | 1.2284 (rough estimate) | | refractive index | 1.5300 (estimate) | | storage temp. | -20°C | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Cryst. | | pka | 10.47±0.40(Predicted) |
| Hazard Codes | N | | Risk Statements | 50 | | Safety Statements | 61 | | RIDADR | UN 3077 9 / PGIII | | WGK Germany | 3 |
| | (-)-TEPHROSIN Usage And Synthesis |
| Uses | Tephrosin as a natural rotenoid obtained from Tephrosia vogelii and displays anticancer activity. | | Definition | ChEBI: A member of the class of rotenones that is 13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one substituted with geminal methyl groups at position 3, hydroxy group at position 7a a
d methoxy groups at positions 9 and 10 (the 7aR,13aR stereoisomer). It is isolated from the leaves and twigs of Antheroporum pierrei and exhibits antineoplastic and pesticidal activities. | | target | ROS | PARP | Autophagy | HSP (e.g. HSP90) | EGFR | Akt | ERK | Caspase | AMPK | mTOR |
| | (-)-TEPHROSIN Preparation Products And Raw materials |
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