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| | Arjunolic acid Basic information |
| Product Name: | Arjunolic acid | | Synonyms: | arjunolic acid;2,3,23-Trihydroxyolean-12-en-28-oic acid;(2alpha,3beta,4alpha)-2,3,23-Trihydroxy-olean-12-en-28-oic acid;Arjulic acid;Olean-12-en-28-oicacid, 2,3,23-trihydroxy-, (2a,3b,4a)-;Arjunolic acid >=95% (LC/MS-ELSD);arjunolicaci;hepatocyte injury,hyperglycemia,Inhibitor,type 1 diabetes,antimicrobial,antioxidant,Reactive Oxygen Species,Antidiabetic,Arjunolic acid,antibacterial,inhibit,Symplocos lancifolia,reactive oxygen | | CAS: | 465-00-9 | | MF: | C30H48O5 | | MW: | 488.7 | | EINECS: | | | Product Categories: | Pentacyclic Triterpenes | | Mol File: | 465-00-9.mol |  |
| | Arjunolic acid Chemical Properties |
| Melting point | 332-334 °C | | Boiling point | 606.0±55.0 °C(Predicted) | | density | 1.19±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Powder | | pka | 4.62±0.70(Predicted) |
| | Arjunolic acid Usage And Synthesis |
| Description | Arjunolic acid is a triterpene that has been found in T. arjuna and has diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in a cell-free assay when used at a concentration of 0.8 mM. Arjunolic acid (20 mg/kg for four days) prevents arsenic-induced decreases in the activity of superoxide dismutase (SOD1), catalase, GST, and glutathione reductase in mouse brain. It reduces tumor growth in an Ehrlich murine spontaneous adenocarcinoma model when administered at doses of 100 and 250 mg/kg for 20 days. Arjunolic acid reduces renal fibrosis and increases in kidney TNF-α and IL-1β levels induced by cisplatin in mice when administered at doses of 100 and 250 mg/kg per day for 10 days. | | Uses | Arjunolic Acid is a naturally occurring terpenoid which displays anti-inflammatory activity as well as protective effects during chemical induced organ pathophysiology. | | Definition | ChEBI: A pentacyclic triterpenoid that is olean-12-en-28-oic acid substituted by hydroxy groups at positions 2, 3 and 23 (the 2alpha,3beta stereoisomer). Isolated from Symplocos lancifolia and Juglans sinensi
, it exhibits antioxidant and antimicrobial activities. |
| | Arjunolic acid Preparation Products And Raw materials |
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